ORIGINAL RESEARCH article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1438569
Visual Outcomes with Two Posterior Chamber Phakic Intraocular Lenses in Myopic Patients: A Contralateral Eye Study Running head: Phakic intraocular lens implantation outcomes
Provisionally accepted
Boliang LiXun ChenMingrui ChengI-Chun LinYinjie JiangYadi LeiGuanghan XuMingwei LiZhiwei Mao
Xingtao Zhou
Xiaoying Wang*- Eye and Ent Hospital, Fudan University, Shanghai, China
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Purpose: Assess the efficacy, safety, and visual quality of two posterior chamber phakic intraocular lenses (PIOL) for myopia correction.Methods: In this randomized double-blind prospective controlled trial, 38 eyes of 19 myopic patients received phakic refractive (PR) IOL in one eye and implantable collamer lens (EVO ICL) in the opposite eye and were followed up for 1 year. Uncorrected distance visual acuity, corrected distance visual acuity, vault, disk halo size, contrast sensitivity, higher-order aberrations, retinal imaging quality, intraocular scattering, and subjective glare/halo perception were measured.Results: At 1 year, mean efficacy indices were 1.03 ± 0.16 (PR) and 1.01 ± 0.15 (ICL), and mean safety indices were 1.18 ± 0.07 (PR) and 1.15 ± 0.09 (ICL). The PR group had lower vaults than those of the ICL group at 1 year (342.63 ± 153.94 μm vs. 470.00 ± 230.31 μm, P = 0.010). One month postoperatively, the severity of glare/halo was significantly milder in the PR group than that in the ICL group (P = 0.035). However, 1 year postoperatively, no significant differences were observed in the severity of glare/halo between the two groups. Conclusions: PR implantation is a safe and effective treatment option for myopia. The PR group exhibited lower vaults than those of the ICL group. The PR group had milder glare/halo in the early postoperative period compared to the ICL group, though long-term differences were not significant.
Keywords: PIOL, Implantable collamer lens, Refractive outcomes, visual quality, Myopia
Received: 26 May 2024; Accepted: 23 Jun 2025.
Copyright: © 2025 Li, Chen, Cheng, Lin, Jiang, Lei, Xu, Li, Mao, Zhou and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaoying Wang, Eye and Ent Hospital, Fudan University, Shanghai, China
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