ORIGINAL RESEARCH article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1505401
This article is part of the Research TopicEnhancing Patient Outcomes After Cataract, Corneal and Refractive SurgeryView all 13 articles
Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration
Provisionally accepted
- Oftalvist Clinic, Alicante, Spain
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To evaluate visual function in eyes with age-related macular degeneration (AMD) implanted with a non-diffractive enhanced depth-of-focus (EDOF) intraocular lens (IOL) after cataract surgery.Design: Prospective, observational, non-randomised clinical study.Methods: Twenty-two eyes from 22 patients diagnosed with AMD and cataracts were submitted to standard cataract surgery with a non-diffractive EDOF IOL implantation (AcrySof IQ Vivity). We measured monocular uncorrected and best-corrected-distance visual acuity (UDVA and CDVA), uncorrected-and distance-corrected-intermediate visual acuity (UIVA and DCIVA), uncorrected-and distance-corrected-near visual acuity (UNVA and DCNVA), manifest refractive spherical equivalent (MRSE) and cylinder, monocular defocus curve and patient-reported outcome questionnaires (Catquest-9SF and NEI VFQ-25). Follow-up visits were carried out at 1-, 3-and 6-months post-surgery.Results: At 6-months post-surgery all eyes were within ±0.50 D with a mean MRSE of -0.19±0.20 D, 95.45% had a refractive cylinder of ≤0.50 D with a mean cylinder of -0.24±0.27 D. The mean values of postoperative monocular CDVA, DCIVA, and DCNVA were 0.02±0.08, 0.16±0.11, and 0.26±0.15 logMAR, respectively. The defocus curve showed good visual acuity at distance and intermediate with a depth-of-focus of about 1.60 D. 81.82% of patients did not report any difficulty with their vision in their everydaylife and 86.36% reported being quite satisfied to very satisfied with their current vision. The NEI VFQ-25 showed that all values improved significantly (p<0.05) after the surgery in the different parameters analysed except for ocular pain (p=0.390) and colour vision (p=0.333).Conclusions: The use of a non-diffractive EDOF IOL in AMD eyes with cataracts is a safe and effective surgical approach for visually correcting aphakia, providing good visual acuity at far and intermediate distances. Our outcomes support the use of non-diffractive EDOF IOLs in patients with AMD diagnosed with cataracts aiming to obtain spectacleindependence at far and intermediate distances.
Keywords: age-related macular degeneration, enhanced depth-of-focus, Cataracts, Intraocular lens, Patient Satisfaction
Received: 02 Oct 2024; Accepted: 27 May 2025.
Copyright: © 2025 Elvira, Devesa, Elvira-Giner, Tañá-Sanz, Orts-Vila and Tañá-Rivero. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Pedro Tañá-Rivero, Oftalvist Clinic, Alicante, Spain
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