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ORIGINAL RESEARCH article

Front. Med.

Sec. Nephrology

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1506188

This article is part of the Research TopicInfections in the Intensive Care Unit - Volume IIIView all 17 articles

Establishment and Application of an Infection Prevention and Control System for Patients Undergoing Continuous Renal Replacement Therapy

Provisionally accepted
Zhongjing  ZhaoZhongjing Zhao*Huijie  ZhaoHuijie ZhaoYang  YangYang YangYunzong  WangYunzong WangXia  ZhaoXia Zhao
  • Xuanwu Hospital, Capital Medical University, Beijing, China

The final, formatted version of the article will be published soon.

Background: Continuous Renal Replacement Therapy (CRRT) is essential for critically ill patients but carries a high risk of hospital-acquired infections.Implementing an effective infection prevention and control system is critical for improving patient safety.Methods: This study utilized the Delphi method to develop a comprehensive infection prevention and control indicator system specifically designed for CRRT patients. A total of 126 patients treated at Xuanwu Hospital, Capital Medical University from January to December 2023 were included in the study. They were divided into a control group (n=62), which received standard care, and an observation group (n=64), which adopted the newly developed indicator system. Adverse event rates and nursing quality scores were compared between the two groups.Results: The final indicator system consisted of 3 primary, 9 secondary, and 27 tertiary indicators, with expert consensus reflected by a reliability coefficient of 0.795.The observation group demonstrated a significantly lower incidence of adverse events (3.12% vs. 16.12%, P<0.05) and higher nursing quality scores across three dimensions (basic care, equipment management, and nursing safety) compared to the control group (P<0.05).The infection prevention and control indicator system for CRRT patients exhibited strong reliability and scientific validity. Its implementation led to a significant reduction in infection rates and improvements in nursing quality, highlighting its potential for broader clinical adoption.

Keywords: continuous renal replacement therapy, Infection prevention and control, Nursing quality, Delphi method, Clinical Management

Received: 04 Oct 2024; Accepted: 12 Jun 2025.

Copyright: © 2025 Zhao, Zhao, Yang, Wang and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Zhongjing Zhao, Xuanwu Hospital, Capital Medical University, Beijing, China

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