CASE REPORT article
Front. Med.
Sec. Obstetrics and Gynecology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1527778
Urinary Bladder Paraganglioma in Pregnancy: a Case Report and Literature Review
Provisionally accepted
- 1Department of Urology, Weifang People's Hospital, Weifang, Shandong Province, China
- 2Shangdong Provincial Key Laboratory for Prevention and Treatment of Urological Diseases in Medicine and Health, Weifang, China
- 3Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
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Urinary bladder paragangliomas (UBPs) are rare tumors of chromaffin tissue originating from sympathetic innervation of the bladder wall. It constitutes less than 0.05% of bladder tumors and 0.7% of all paragangliomas. UBP occurring during pregnancy is extremely rare. Hypertensive disorders of pregnancy due to paraganglioma increase the risk of adverse maternal and fetal outcomes. Herein, we report a case of UBP in a 28-year-old woman at 34 weeks' gestation. The baby was successfully delivered, and bladder tumor was removed through partial cystectomy at the same time. In addition, we perform a literature review of paragangliomas in pregnancy, as there are only a few case reports of such diseases and there is no consensus on standard treatment. This study aims to contribute to improving the diagnosis and treatment of UBP in pregnancy.
Keywords: Urinary Bladder Tumor1, Pregnancy2, Paraganglioma3, hypertension4, Rare disease5. (Min.5-Max. 8
Received: 22 Mar 2025; Accepted: 25 Jul 2025.
Copyright: © 2025 Sun, Chen, Li and Qiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Liang Qiao, Department of Urology, Weifang People's Hospital, Weifang, 261000, Shandong Province, China
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