CASE REPORT article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1546953
A case of unexplained retinoschisis
Provisionally accepted
- Qingdao Hospital, University of Health and Rehabilitation Sciences（Qingdao Municipal Hospital）, Qingdao, China
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Background: Retinoschisis is characterized by separation of the neurosensory retina into two layers. The traditional pars plana vitrectomy with internal limiting membrane peeling and macular buckling have been shown to resolve retinoschisis. We report a case of unknown cause of retinoschisis in a young adult. Case presentation: A 24-year-old man presented with an 18-day history of metamorphopsia and blurred vision in his left eye. Optical coherence tomography revealed retinoschisis in the macular, the temporal side of the macular and near the superior and inferior vascular arches. The patient was treated with oral corticosteroids. His clinical characteristics and status of retinoschisis were monitored at each visit. The retinoschisis initially became aggravated; however, it had completely resolved by the 40-day follow-up visit. Conclusions: Clinicians should be aware that for the patients with clinically identified PVD without VMT, follow-up observation or empirical treatment with glucocorticoids can be considered to observe the disease outcome.
Keywords: Retinoschisis, corticosteroid, etiology, case report, Inflammation
Received: 17 Dec 2024; Accepted: 02 Sep 2025.
Copyright: © 2025 Wang, Zhang, Yuan, Zhao and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zhanyu Zhou, Qingdao Hospital, University of Health and Rehabilitation Sciences（Qingdao Municipal Hospital）, Qingdao, China
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