CLINICAL TRIAL article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1554832
This article is part of the Research TopicIntraocular Pressure Evaluation and Confounding ParametersView all articles
Surgical outcomes of phacoemulsification with different fluidics systems (Centurion with Active Sentry vs. Centurion gravity) in cataract patients with eye axial length above 26mm
Provisionally accepted
Yinan Liu
Xiaoyong Chen*- Peking University Third Hospital, Haidian, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: During cataract phacoemulsification surgery, the Alcon Centurion with Active Sentry can achieve a more stable anterior chamber, which allows a lower intraocular pressure (IOP) setting than Centurion under gravity mode. In this randomized controlled trial, we compared these two systems' impact on high myopia patients' macular blood perfusion under different IOP settings.To evaluate intra-op and post-op clinical performance of the Alcon Centurion with Active Sentry and under gravity mode in cataract patients with eye axial lengths > 26mm.Methods: Fifty-two eyes of 43 cataract patients with axial lengths > 26mm were enrolled and randomly divided into the active fluidics system (AFS) group using a Centurion Active Sentry handpiece under 30 mmHg IOP setting (26 eyes) and the gravity fluidics system (GFS) group in gravity mode under 80 cmH2O IOP setting (26 eyes). Intraoperative parameters, visual acuity, parafoveal macular vessel density and macular thickness were analyzed.We observed no significant differences in best corrected visual acuity (BCVA), macular thickness, cumulative dissipated energy (CDE), total case time, as well as ophthalmic viscoelastic devices (OVDs) usage between the two groups. However, we found less pain complaints during surgeries and a more stable macular vessel density post-surgery in the AFS group than in the GFS group, implying higher intraoperative comfort levels and less retinal ischemia during cataract surgery using Centurion with Active Sentry under low IOP settings.Owing to a lower IOP setting, Centurion Vision System with Active Sentry handpiece causes less retinal ischemia and pain perception during phacoemulsification for high myopia patients.
Keywords: High myopia, Alcon Centurion, Active Sentry, Phacoemulsification, Macular vessel density
Received: 03 Jan 2025; Accepted: 30 May 2025.
Copyright: © 2025 Liu and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaoyong Chen, Peking University Third Hospital, Haidian, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.