CASE REPORT article
Front. Med.
Sec. Gastroenterology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1557305
A female patient with gastrointestinal perforation, acute diffuse peritonitis, and Crohn's disease needs homeostasis management
Provisionally accepted
- Wenzhou Medical University, Wenzhou, China
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A 47-year-old married woman presented with abdominal discomfort, distension, and nausea following a two-day episode of constipation accompanied by reduced urine output. Upon her admission, a physical assessment indicated tachycardia and abdominal sensitivity, while imaging examinations corroborated gastrointestinal perforation along with signs of acute diffuse peritonitis.The patient had a prior history of Crohn's disease and had been off medication for over a year. The initial surgical intervention entailed bowel resection and adhesiolysis; however, postoperative complications arose, prompting a second operation due to suspected anastomotic leakage and a severe infection. In spite of these challenges, the patient received intensive care, nutritional support, and treatment for short bowel syndrome. Over span of a month, her health significantly improved, and she was ultimately discharged with ongoing management for her Crohn's disease. This case underscores the intricacies involved in addressing intestinal perforations in patients with pre-existing Crohn's disease and highlights the imperative for prompt surgical action and comprehensive postoperative care.
Keywords: Gastrointestinal perforation, Acute diffuse peritonitis, Crohn's disease, homeostasis management, Acute renal failure
Received: 08 Jan 2025; Accepted: 09 Jul 2025.
Copyright: © 2025 Fei, Yu, Yan and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wan-Neng Yan, Wenzhou Medical University, Wenzhou, China
Jin-Liang Dong, Wenzhou Medical University, Wenzhou, China
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