MINI REVIEW article
Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1567229
This article is part of the Research TopicExploring Clinical Outcomes and Treatment Predictors in Septic ArthritisView all articles
The impact of comorbidities on the prognosis of patients with septic arthritis
Provisionally accepted
Muhammad Umair Akhtar
Zaid Chilmeran
Abu-Baker Khalid Sharafeldin
Yahya Mostafa Waly
Mustafa Tariq Khan
Salim Fredericks*- Royal College of Surgeons in Ireland (Bahrain), Al Muharraq, Bahrain
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Septic arthritis is a serious infection that can lead to joint destruction, sepsis, and high mortality rates, particularly in elderly patients and those with comorbid conditions. Comorbidities such as diabetes, rheumatoid arthritis, chronic kidney disease, and liver disease can complicate the diagnosis, treatment, and overall prognosis of the disease. These conditions may impair immune function, delay diagnosis, and hinder effective antimicrobial therapy, thereby increasing the risk of severe complications and poor outcomes. This review explores the impact of comorbidities on the prognosis of patients with septic arthritis, emphasizing the need for tailored management strategies to improve outcomes in this vulnerable population. Understanding the interplay between comorbid conditions and septic arthritis is essential for optimizing treatment approaches and enhancing patient care.
Keywords: septic arthritis, Comorbidities,, prognosis, Mortality, Treatment outcomes
Received: 27 Jan 2025; Accepted: 26 May 2025.
Copyright: © 2025 Akhtar, Chilmeran, Sharafeldin, Waly, Khan and Fredericks. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Salim Fredericks, Royal College of Surgeons in Ireland (Bahrain), Al Muharraq, Bahrain
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