CASE REPORT article
Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1568219
Mild encephalitis/encephalopathy with reversible corpus callosum lesion associated with listeria infection with meningoencephalitis: a case report
Provisionally accepted
- 1Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China
- 2Second People’s Hospital of Hunan Province, Yuhua, Hunan Province, China
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Dear Editor, I wish to submit an original review article entitled "Mild Encephalitis/Encephalopathy with Reversible Corpus Callosum Lesion Associated with Listeria Infection with Meningoencephalitis: A Case Report" for consideration by Frontiers in Medicine. I confirm that this work is original and has not been published elsewhere, nor is it currently under consideration for publication elsewhere. In this article, we present the case of a 65-year-old immunocompetent female patient who presented with headache, fever, and vomiting. Cerebrospinal fluid (CSF) culture and metagenomic next-generation sequencing (mNGS) were positive for L. monocytogenes. Brain MRI revealed abnormal signals in the leptomeninges and the splenium of the corpus callosum. During her hospitalization, the patient experienced recurrent electrolyte disturbances. She was treated with meropenem for infection and received symptomatic treatment. Her symptoms significantly improved during the hospital stay. Follow-up by phone for one year after discharge revealed no recurrence of L. monocytogenes meningoencephalitis. Additionally, we explored the correlation with the patient's co-occurrence of Mild Encephalitis/Encephalopathy with Reversible Splenial Lesion (MERS) in this patient.
Keywords: Listeria monocytogenes, Meningoencephalitis, MERS, Adult Patients With Normal Immunity, case report
Received: 30 Jan 2025; Accepted: 16 Jun 2025.
Copyright: © 2025 Liang, peng, Luo and Tang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiayu Tang, Second People’s Hospital of Hunan Province, Yuhua, 410007, Hunan Province, China
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