ORIGINAL RESEARCH article
Front. Med.
Sec. Geriatric Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1572131
Elevated neutrophil to high-density lipoprotein ratio predicts pneumonia in patients with Intracerebral Hemorrhage
Provisionally accepted
Yuning Feng1*
Wenyao Cui2Yangchun Xiao1Xin Cheng1Lvlin Chen1Liyuan Peng3Chao You1Fang Fang2Li Li2Dianxiang Lu1Yu Zhang1*- 1Affiliated Hospital and Clinical Medical College of Chengdu University, Chengdu, China
- 2West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
- 3First People's Hospital of Longquanyi District, Chengdu, Sichuan Province, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: Pneumonia is a common and serious complication among patients with intracerebral hemorrhage (ICH), contributing to increased morbidity and mortality. Early identification of patients at high risk for pneumonia is essential for implementing preventive strategies and improving outcomes.The neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) has emerged as a novel marker of systemic inflammation with potential predictive value. This study examines whether elevated NHR is associated with an increased risk of pneumonia in patients with ICH, aiming to evaluate NHR as a practical biomarker for early risk prediction.Methods: This retrospective multicenter cohort study included patients diagnosed with intracerebral hemorrhage (ICH) from three hospitals:
Keywords: neutrophil-to-high-density lipoprotein cholesterol ratio, Pneumonia, intracerebral hemorrhage, biomarker, Inflammation
Received: 06 Feb 2025; Accepted: 09 Jun 2025.
Copyright: © 2025 Feng, Cui, Xiao, Cheng, Chen, Peng, You, Fang, Li, Lu and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yuning Feng, Affiliated Hospital and Clinical Medical College of Chengdu University, Chengdu, China
Yu Zhang, Affiliated Hospital and Clinical Medical College of Chengdu University, Chengdu, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.