ORIGINAL RESEARCH article
Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1573347
Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
Provisionally accepted
- 1Sixth Affiliated Hospital of Xinjiang Medical University, Ürümqi, China
- 2Xinjiang Medical University, Sixth Affiliated Hospital of Xinjiang Medical University, Ürümqi, China
- 3Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi, Xinjiang, China
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OBJECTIVE: This study aims to evaluate the clinical effectiveness of minimally invasive versus conventional open posterior methods for the excision of brucellosis lesions in the context of spondylitis treatment. The findings are intended to inform and guide clinical practice.METHODS: Forty-three patients with brucellosis spondylitis who attended our hospital from January 2020 to June 2023 were selected and divided into minimally invasive endoscopic brucellosis lesion removal (group A) n=18 and traditional open lesion removal group (group B) n=25 according to the operation type.All patients were given antibiotic treatment before operation. Analyze the relevant clinical indicators.Results: ①There were no statistically significant differences (P > 0.05) between the two groups in terms of age, gender, body mass index (BMI), medical history, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, hemoglobin (Hb), visual analog scale (VAS) score, Oswestry Disability Index (ODI) score and recurrence rate.②The operation time (P<0.012), intraoperative blood loss (P<0.012), and postoperative hospital stay (P<0.012) in group A were significantly shorter than those in group B, and the differences between the two groups were statistically significant (P < 0.05). No significant differences were observed in the remaining outcome measures.CONCLUSION: The results of this study showed that minimally invasive endoscopic brucellosis lesion removal could achieve the same efficacy as compared with traditional open posterior lesion removal, but minimally invasive surgery has the advantages of shorter operative time, lower intraoperative haemorrhage and more obvious advantages in postoperative rehabilitation, etc., which makes it clinically feasible and effective procedure.
Keywords: Brucellosis, brucellosis spondylitis, Lesion removal, Endoscopy, Minimally invasive
Received: 08 Feb 2025; Accepted: 25 Jun 2025.
Copyright: © 2025 Siyiti, Lin, Siyiti and Sui. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiangtao Sui, Sixth Affiliated Hospital of Xinjiang Medical University, Ürümqi, China
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