ORIGINAL RESEARCH article
Front. Med.
Sec. Obstetrics and Gynecology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1576761
This article is part of the Research TopicIntegrating Nutrition in Cancer Therapy: Approaches to Improve Patient Outcomes and SurvivalView all 6 articles
Clinical efficacy of ERAS plus enteral nutrition in patients undergoing laparoscopic surgery for gynecologic malignancies
Provisionally accepted
- 1Zigong Fourth People's Hospital, Zigong, Sichuan, China
- 2Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China
- 3Department of Gynecology, the Affiliated Changzhou Second Peoples Hospital of Nanjing Medical University, Changzhou, Jiangsu 213000, PR China;, Changzhou, China
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Objective: To enhance postoperative recovery in gynecological malignancies by evaluating the clinical efficacy and safety of Enhanced Recovery After Surgery (ERAS) combined with enteral nutrition. Methods: This study included 127 patients with gynecological malignancies treated at Zigong Fourth People's Hospital between January and December 2022. Based on patient preference, 60 were placed in the study group (ERAS + enteral nutrition) and 67 in the control group (traditional care). The two groups were compared on postoperative protein levels, electrolyte balance, and recovery indicators, including the time to first anal exhaust, defecation, and hospital stay duration. Additionally, preoperative thirst, hunger, anxiety scores, postoperative complications, and total hospitalization costs were evaluated. Results: The study group had higher postoperative total protein (66.59±10.97 g/L) and albumin (43.47±51.27 g/L) than the control group, with a significantly lower incidence of hypoproteinemia (18.33% vs. 50.75%, P < 0.05). There were no significant differences in hemoglobin, lymphocyte count, or electrolytes. The study group recovered bowel function earlier than the control group, with significant differences in defecation time (P < 0.05). No significant differences were observed in anal exhaust time, hospital stay, complications, or total costs. The study group had better anxiety, thirst, and hunger scores (P < 0.05). Conclusions: ERAS combined with enteral nutrition is safe and effective for gynecological cancer surgery, reducing hypoproteinemia, promoting gastrointestinal recovery, and improving patient experience and psychological well-being.
Keywords: Eras, Enteral Nutrition, gynecological malignant tumor, laparoscopic surgery, Enhanced recovery after surgery
Received: 14 Feb 2025; Accepted: 08 Sep 2025.
Copyright: © 2025 xia, Zhang, Su, Zhou, Liu, Lu and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiming Chen, Department of Gynecology, the Affiliated Changzhou Second Peoples Hospital of Nanjing Medical University, Changzhou, Jiangsu 213000, PR China;, Changzhou, China
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