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HYPOTHESIS AND THEORY article

Front. Med.

Sec. Translational Medicine

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1588062

Bridging the gap between CVD and COVID-19: the oxidized LDL hypothesis

Provisionally accepted
  • Department of Biology, Faculty of Arts and Sciences, University of Balamand, El-Koura, Lebanon

The final, formatted version of the article will be published soon.

Dear editor, I wish to submit an original hypothesis article entitled "Bridging the gap between CVD and COVID-19: the modified LDL hypothesis" for consideration in "Frontiers in medicine".I confirm that this work is original and has not been published elsewhere, nor is it currently under consideration for publication elsewhere.Since little is known about the relationship between dyslipidemia, mainly the modification of LDL, CVD and COVID-19, I hereby hypothesize, for the first time, that Mox-LDL may be considered as a major factor that links the latter pathologies through its role in fibrinolytic pathways. I believe that this manuscript is appropriate for publication in "Frontiers in medicine" because it perfectly goes along with its overall aim and scope, especially that the work is concise, straight to the point and novel in presenting a brief overview onto Mox-LDL pro-atherosclerostic pathways and their implications for COVID-19.

Keywords: Jalil Daher: Conceptualization, Writingoriginal draft, Writingreview & editing COVID-19, endothelial dysfunction, Atherosclerosis, cardiovascular disease, Dyslipidemia, HDL

Received: 05 Mar 2025; Accepted: 22 Jul 2025.

Copyright: © 2025 Daher. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Jalil Daher, Department of Biology, Faculty of Arts and Sciences, University of Balamand, El-Koura, Lebanon

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