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ORIGINAL RESEARCH article

Front. Med.

Sec. Precision Medicine

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1589707

RaNet: A Residual Attention Network for Accurate Prostate Segmentation in T2-Weighted MRI

Provisionally accepted
  • 1College of Computer Science, Chongqing University, Chongqing, China
  • 2Department of Computer Engineering, College of Computer, Qassim University, buraydah, Saudi Arabia
  • 3Department of Cybersecurity, College of Computer, Qassim University, Buraydah, Saudi Arabia

The final, formatted version of the article will be published soon.

Accurate segmentation of the prostate in T2-weighted MRI is critical for effective prostate diagnosis and treatment planning. Existing methods often struggle with the complex textures and subtle variations in the prostate. To address these challenges, we propose RaNet (Residual Attention Network), a novel framework based on ResNet50, incorporating three key modules: the DilatedContextNet (DCNet) encoder, the Multi-Scale Attention Fusion (MSAF), and the Feature Fusion Module (FFM). The encoder leverages residual connections to extract hierarchical features, capturing both fine-grained details and multi-scale patterns in the prostate. The MSAF enhances segmentation by dynamically focusing on key regions, refining feature selection and minimizing errors, while the FFM optimizes the handling of spatial hierarchies and varying object sizes, improving boundary delineation. The decoder mirrors the encoder's structure, using deconvolutional layers and skip connections to retain essential spatial details. We evaluated RaNet on a prostate MRI dataset PROMISE12 and ProstateX , achieving a DSC of 98.61 and 96.57 respectively. RaNet also demonstrated robustness to imaging artifacts and MRI protocol variability, confirming its applicability across diverse clinical scenarios. With a balance of segmentation accuracy and computational efficiency, RaNet is well suited for real-time clinical use, offering a powerful tool for precise delineation and enhanced prostate diagnostics.

Keywords: RaNet, deep learning, Refine Feature Selection, Medical image segmentation, prostate cancer, Feature fusion

Received: 07 Mar 2025; Accepted: 06 Jun 2025.

Copyright: © 2025 Arshad, Wang, Wajeeh Us Sima, Shaikh, Alkhalaf and Alturise. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Chengliang Wang, College of Computer Science, Chongqing University, Chongqing, 400044, China
Salem Alkhalaf, Department of Computer Engineering, College of Computer, Qassim University, buraydah, Saudi Arabia

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