CASE REPORT article
Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1591785
Orientia tsutsugamushi meningitis patient with tuberculous meningitis complications: a case report
Provisionally accepted
- 1Yueyang Central Hospital, Yueyang City，Hunan Province, China
- 2Yueyang Hospital of Traditional Chinese Medicine,, Yueyang City, Hunan Province,, China
- 3Weifang People's Hospital, Weifang, Shandong Province, China
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Scrub typhus (ST) is caused by Orientia tsutsugamushi infection through chigger mite bites, resulting in febrile disease. Clinical manifestations are complex and may be combined with other microbial infections. This report describes a rare case of scrub typhus meningitis and tuberculous meningitis. The patient had fever and chills, and also had a dull reaction on admission. Timely diagnosis and appropriate antibiotic therapy are critical for avoiding complications and lowering mortality.Next-generation sequencing (NGS) provided diagnostic clues, and the diagnosis of scrub typhus meningitis combined with tuberculous meningitis was quickly clarified. The patient's symptoms were relieved after appropriate treatment. NGS can be a useful diagnostic technique for early clinical infections.
Keywords: ：scrub typhus, Orientia tsutsugamushi meningitis, tuberculous meningitis, Next-generation sequencing, a, A rare case
Received: 11 Mar 2025; Accepted: 30 May 2025.
Copyright: © 2025 Tan, Zou, Yang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Anchun Liu, Yueyang Central Hospital, Yueyang City，Hunan Province, China
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