Your new experience awaits. Try the new design now and help us make it even better

CASE REPORT article

Front. Med.

Sec. Infectious Diseases: Pathogenesis and Therapy

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1593385

Schaalia turicensis Endometritis in a Diabetic Patient: MALDI-TOF MS Overcomes Diagnostic Barriers in a Non-IUD-Associated Case

Provisionally accepted
Yan  LiuYan LiuMei  LiMei LiYunyun  DingYunyun DingYong  GaoYong GaoTuantuan  LiTuantuan Li*Xiaowu  WangXiaowu Wang*
  • The Second People's Hospital of Fuyang city, Fuyang, Fuyang, Jiangsu Province, China

The final, formatted version of the article will be published soon.

Schaalia (Formerly Actinomyces) turicensis is a single-cell prokaryotic microorganism and a common component of the normal human oral flora. If it enters other parts and causes infection, it may lead to actinomycosis. We present the case of a 74-year-old female patient from Fuyang who developed bacterial endometritis due to Schaalia turicensis. The bacterial culture of painless cervical dilation with drainage and curettage showed slow-growing, Gram-positive rods, which were identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) as Schaalia turicensis. The patient was initially treated empirically with cefathiamidine and tinidazole for 3 days, with no improvement of symptoms. Subsequently, the treatment regimen was adjusted to intravenous infusion of amoxicillin and clavulanate potassium (1.2 g) every 8 hours for 7 days. Resulted in significant alleviation of the patient's symptoms. Clinicians should be aware of other types of infections that may be caused by Schaalia turicensis.

Keywords: Endometritis, Schaalia turicensis, Microbial identification, treatment regimen, case report

Received: 18 Mar 2025; Accepted: 18 Jul 2025.

Copyright: © 2025 Liu, Li, Ding, Gao, Li and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Tuantuan Li, The Second People's Hospital of Fuyang city, Fuyang, Fuyang, Jiangsu Province, China
Xiaowu Wang, The Second People's Hospital of Fuyang city, Fuyang, Fuyang, Jiangsu Province, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.