CASE REPORT article
Front. Med.
Sec. Nephrology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1597849
This article is part of the Research TopicDeciphering Host-Pathogen Interactions in Tuberculosis: Implications for Diagnostics and TherapeuticsView all 9 articles
Case report: Papillary Renal Cell Carcinoma Complicated by Ipsilateral Renal Tuberculosis
Provisionally accepted
Ni Fu1*
Zhong Tian1Cheng Zhu1
Tingting Yang2
Shi Cheng Chen1Zhongcong He1Guang Han1Zhouhui Chen1
Zhang Neng2*
Bo Yu1- 1Department of Urology, Second Affiliated Hospital of Zunyi Medical University, Zunyi, China
- 2Department of Urology, Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou Province, China
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Papillary renal cell carcinoma (PRCC) complicated by ipsilateral renal tuberculosis (TB) represents an exceptionally rare and complex clinical condition. Renal TB is the most common form of urogenital TB, while PRCC is the most prevalent histological subtype of non-clear cell renal cell carcinoma (RCC). In this study, we present the first reported case of PRCC complicated by ipsilateral renal TB, where the patient exhibited low back pain without hematuria. Initial imaging studies indicated a space-occupying lesion in the left kidney, raising suspicion of renal tumors. Subsequent postoperative pathology, immunohistochemical staining, and tuberculosis PCR results confirmed the diagnosis of PRCC complicated by ipsilateral renal TB.
Keywords: Renal cell carcinoma, Renal tuberculosis, tumor, Papillary renal cell carcinoma, renal cell carcinoma with renal tuberculosis
Received: 21 Mar 2025; Accepted: 31 Jul 2025.
Copyright: © 2025 Fu, Tian, Zhu, Yang, Chen, He, Han, Chen, Neng and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ni Fu, Department of Urology, Second Affiliated Hospital of Zunyi Medical University, Zunyi, China
Zhang Neng, Department of Urology, Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou Province, China
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