ORIGINAL RESEARCH article
Front. Med.
Sec. Hepatobiliary Diseases
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1598579
An in-depth analysis of research on posthepatectomy liver failure (2006-2024): Exploring trends and future directions through a bibliometric approach
Provisionally accepted
Yachen Wu
Jiangtao Li
Zhaohai LiuMengliang JiangHao LiangSajid Ameer
Zhu ZhuZhangtao Long
Zhu Zhu*Xiaoming Dai*- The First Affiliated Hospital, University of South China, Hengyang, China
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The Web of Science Core Collection database was searched for literature related to PHLF from 2006 to 2024. The authors, publishing institutions, countries, cited literature, journals, and keywords of the included studies were utilized for bibliometric analysis using CiteSpace and VOSviewer.The analysis included 986 publications authored by 296 researchers from 60 countries and 246 institutions across 292 journals. The most prolific authors were Aldrighetti Luca, Cescon Matteo and Sparrelid Ernesto. The institutions with the most publications were Naval Medical University, Ruprecht Karls University Heidelberg, and the University of Amsterdam. The countries with the largest number of publications were China, Japan, and the United States. The most commonly cited literature was "posthepatectomy liver failure: a definition and grading" by the International Study Group of Liver Surgery (ISGLS). Annals of Surgery ranked first in the number of co-citations among journals. Currently, the research hotspots of PHLF focus primarily on novel surgical procedures such as liver venous deprivation, associating liver partition and portal vein ligation for staged hepatectomy, and the prediction of PHLF.Our study elucidates the global research status of PHLF and clarifies the relevant research hotspots and trends, providing clinicians and researchers with a better understanding of the state of the art and directions for future research.Bibliometric analysis was used to explore the global research landscape of posthepatectomy liver failure (PHLF).This study investigates various elements of publications in the field of PHLF, including prolific authors, publishing institutions, countries, frequently cited literature, journals, and important keywords, which offer clinicians and researchers a better understanding of research hotspots and trends.Using a single database or language might result in a selection bias that underestimates the output in this research field.
Keywords: Bibliometric analysis through science mapping and performance analysis. Data sources: The Web of Science Core Collection PHLF, hotspots, Trends, bibliometric analysis, Visualization analysis
Received: 23 Mar 2025; Accepted: 30 Jul 2025.
Copyright: © 2025 Wu, Li, Liu, Jiang, Liang, Ameer, Zhu, Long, Zhu and Dai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zhu Zhu, The First Affiliated Hospital, University of South China, Hengyang, China
Xiaoming Dai, The First Affiliated Hospital, University of South China, Hengyang, China
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