ORIGINAL RESEARCH article
Front. Med.
Sec. Hematology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1599519
Application of Predonation Hydration for Vasovagal Reactions during Blood Donation: A Bibliometric Analysis (2004-2023)
Provisionally accepted
- 1Hebei Provincial Blood Center, Shijiazhuang, China
- 2Beijing Tong zhou Central Blood Station, Beijing, China
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Background: Vasovagal reaction (VVR) is one of the prevalent adverse reactions encountered during voluntary blood donation, posing a risk to subsequent donations by the same individuals. Here, we present a bibliometric study aimed at mitigating VVRs. Methods: This study retrieved pertinent publications on the correlation between predonation hydration and vasovagal reactions from the Web of Science Core Collection (WoSCC) database from 2004 to 2023. Bibliometric analysis was conducted employing bibliometrix R, VOSviewer, and CiteSpace. Results: This study encompassed 241 papers across 31 countries and 387 research institutions. Notably, the University of Bucharest (Romania, n=12, 4.9%), the Australian Red Cross (Australia, n=10, 4.1%), the University of Queensland (Australia, n=10, 4.1%), Wayne State University (USA, n=6, 2.5%), and Ohio State University (USA, n=5, 2.1%) emerged as the top five contributors in publication output. The journal Transfusion was the most prolific publication venue in this field. Authors Thijsen, Amanda, and Deju, R. were identified as the most prolific contributors in this area. Over the past three years, research trends have predominantly focused on fear, complications, management, and hydration. Conclusion: This marks the first comprehensive overview of bibliometric research aimed at understanding the preventive and mitigative effects of predonation hydration on VVR. Predonation hydration as a strategy to prevent or alleviate VVR is currently the focal point of research interest. Our findings suggest that predonation hydration is a promising, low-cost approach to enhance donor safety and retention, although standardization of protocols is needed.
Keywords: predonation hydration, VVR, Voluntary blood donation, VOSviewer, Bibliometrix, Citespace
Received: 25 Mar 2025; Accepted: 06 Oct 2025.
Copyright: © 2025 Wang, Li, Niu, Shi, Liu, Li, Li and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Cong Wang, cw13230444522@outlook.com
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