ORIGINAL RESEARCH article
Front. Med.
Sec. Family Medicine and Primary Care
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1599857
Health state utility values and associated complication-related difference in community-based adults with type 2 diabetes in Nanjing China: a cross-sectional study
Provisionally accepted
- 1Nanjing Center for Disease Control and Prevention, Nanjing, China
- 2International Peace Maternity and Child Health Hospital, Shanghai, Shanghai Municipality, China
- 3Jiangsu Provincial Center for Disease Control And Prevention, Nanjing, Jiangsu Province, China
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ObjectiveThis study aimed to derive health state utility values (HSUVs) in community-based adults with type 2 diabetes from Nanjing, China, and to examine the differences associated with diabetes-related complications.MethodsA cross-sectional study employing a multi-stage random sampling method was conducted in Nanjing, China, in 2024. A total of 2153 participants were finally included in the analysis. The Chinese version of EQ-5D-3L was used to assess health states, and the corresponding China value set was applied to convert these health states into HSUVs. Participants’ demographic characteristics and complication profiles were collected via a standardized questionnaire. Unadjusted and adjusted HSUV estimates were generated using multiple linear regression models with robust standard errors.ResultsIn the sample, 73.39% reported no problem in all five dimensions of the EQ-5D-3L, and none reported severe problems in any dimension. The mean overall HSUV was 0.9672. The unadjusted analyses showed that participants with any complication had lower HSUVs than those without any complication (all p values < 0.001). In the fully adjusted model, participants with eye-related, cardiovascular, cerebrovascular and other complications (e.g., mental and oral diseases) were associated with decrements in HSUVs (all p values < 0.05). Additionally, marital status and employment were identified as significant predictors of HSUVs (all p values < 0.05).ConclusionsOur study suggests that health utility is not significantly impacted in community-based adults with type 2 diabetes in Nanjing, China. However, people with eye-related, cardiovascular and cerebrovascular complications may require additional attention and care to mitigate decrements in health utility.
Keywords: Health utility, diabetes, Community, adults, China
Received: 25 Mar 2025; Accepted: 21 Jul 2025.
Copyright: © 2025 Huang, Xie, Wang, Fan, Sun, Zhang, Yang and Shen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Huafeng Yang, Nanjing Center for Disease Control and Prevention, Nanjing, China
Ya Shen, Jiangsu Provincial Center for Disease Control And Prevention, Nanjing, 210028, Jiangsu Province, China
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