ORIGINAL RESEARCH article
Front. Med.
Sec. Nephrology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1609311
Combined bailing capsule and conventional therapies in the treatment of chronic renal failure: A meta-analysis and economic evaluation
Provisionally accepted
- 1Peking University, Beijing, Beijing Municipality, China
- 2International Research Center for Medicinal Administration, Peking University, Beijing, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Bailing capsules are currently recommended for improving renal function in patients with chronic renal failure (CRF) in China. However, limited research assesses the clinical benefits of Bailing capsules in the context of healthcare resource utilization.Therefore, we conducted this study to compare the efficacy of Bailing capsules combined with conventional therapies and to assess their economic value from the Chinese healthcare system perspective. For the meta-analysis, six bibliographic databases were systematically searched for eligible randomized controlled trials (RCTs) from their inception until May 2025. For the economic evaluation, a Markov model was established to simulate the disease progression of patients over 20 years.The incremental cost-effectiveness ratio (ICER) was measured, and one-way and probabilistic sensitivity analyses were performed to observe model stability. The use of Bailing capsules combined with conventional therapies was associated with a significant reduction in serum creatinine compared to conventional therapies alone
Keywords: chronic renal failure, Bailing capsules, Markov model, cost-effectiveness analysis, Chinese population
Received: 10 Apr 2025; Accepted: 04 Jun 2025.
Copyright: © 2025 He, Li, Zhu and Han. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Sheng Han, International Research Center for Medicinal Administration, Peking University, Beijing, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.