CASE REPORT article
Front. Med.
Sec. Nuclear Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1609837
This article is part of the Research TopicCase Reports in PET Imaging 2024View all articles
Case report: 18 F-FDG PET/CT revealed diffuse pancreatic metastasis in paranasal sinuses rhabdomyosarcoma after treatment improvement
Provisionally accepted
- 1Affiliated Hospital of Zunyi Medical University, Zunyi, China
- 2Dalian Medical University, Dalian, Liaoning, China
- 3Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province, China
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Metastasis of rhabdomyosarcoma (RMS) from primary paranasal sinuses to the pancreas is rare. Herein, we present a rare case of diffuse pancreatic metastasis in a 44-year-old man.He was diagnosed with sinus RMS one year ago and the lesion disappeared after systematic treatment. The patient came to our hospital in November 2022 due to abdominal pain. Abdominal ultrasound showed diffuse enlargement of the pancreas, with enlarged lymph nodes visible around the pancreas and retroperitoneum. He then underwent positron emission tomography/computed tomography (PET/CT) imaging and the results showed that the pancreas had diffusely increased fluorine-18 fluorodeoxyglucose ( 18 F-FDG) uptake, and the surrounding pancreas and retroperitoneal lymph nodes also had increased 18 F-FDG uptake, suggesting a possibility of malignant tumor. Ultimately, a pancreatic puncture biopsy confirmed RMS with pancreatic and abdominal lymph nodes metastasis. Our case suggests that although diffuse metastatic tumors of the pancreas are relatively rare, which should be considered as one of the differential diagnoses for diffuse pancreatic hypermetabolic lesions on PET/CT imaging.
Keywords: Rhabdomyosarcoma, Pancreatic metastasis, 18 F-FDG, PET/CT, Autoimmune pancreatitis
Received: 11 Apr 2025; Accepted: 13 May 2025.
Copyright: © 2025 Hu, Duan, Zhao, Wang and Pan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xianwen Hu, Affiliated Hospital of Zunyi Medical University, Zunyi, China
Dongfeng Pan, Affiliated Hospital of Zunyi Medical University, Zunyi, China
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