ORIGINAL RESEARCH article
Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1612754
This article is part of the Research TopicAdvances in Emergency Interventional Radiology: Techniques, Outcomes, and Future DirectionsView all articles
Lattice Innovative Flow Diverter with Mechanical Balloons: A New Breakthrough and Efficacy Evaluation in the Treatment of Unruptured Intracranial Aneurysms
Provisionally accepted
- 1The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China
- 2Fuxin People's Hospital, Fuxin, China
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Purpose: The Lattice Innovative Flow Diverter with Mechanical Balloons (Lattice FD-MB) provides superior positioning accuracy and wall apposition during deployment, potentially addressing the limitations of traditional mesh stents in treating complex lesions. However, clinical data on the efficacy and safety of the Lattice FD-MB for unruptured intracranial aneurysms (UIAs) remain limited. This study evaluates the effectiveness and safety of the Lattice FD-MB in UIA treatment. Methods: We retrospectively analyzed 29 UIA patients treated with the Lattice FD-MB at our institution between October and October 2024. Postoperative,digital subtraction angiography (DSA) and computed tomography angiography were performed to assess aneurysm occlusion. Clinical follow-up, including modified Rankin Scale (mRS) scores and DSA, was conducted at 3, 6, and 12 months postoperatively. Results: The Lattice FD-MB was successfully deployed in all patients, achieving a 100% procedural success rate with no intraoperative device-related failures. Intraoperative complications occurred in 2 cases (6.9%). Postoperatively, 27 patients (93.1%) showed favorable clinical outcomes, defined as no new neurological deficits or hemorrhagic/ischemic events. At discharge, functional outcomes (mRS) were as follows: mRS 0 (no symptoms) in 23 patients (79.3%), mRS 1 (no significant disability) in 3 patients (10.3%), and mRS 2 (slight disability) in 3 patients (10.3%). During follow-up, the proportion of patients with mRS 0 increased over time: 82.8% (24/29) at 3 months, 86.2% (25/29) at 6 months, and 89.7% (26/29) at 12 months, demonstrating sustained clinical stability and neurological improvement. Conclusion: The Lattice FD-MB appears to be a feasible and safe treatment for UIAs, with promising patient outcomes. Further research is warranted to investigate prognostic factors influencing long-term results after Lattice FD-MB treatment.
Keywords: Lattice FD-MB, Unruptured intracranial aneurysms, Retrospective study, Therapeutic effect, Safety profile
Received: 16 Apr 2025; Accepted: 20 Aug 2025.
Copyright: © 2025 Sun, Peng, Li, Zhang and Wen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zhifeng Wen, The First Affiliated Hospital of China Medical University, Shenyang, 110000, Liaoning Province, China
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