EDITORIAL article
Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1615467
This article is part of the Research TopicEmerging SARS-COV-2 Variants: Genomic Variations, Transmission, Pathogenesis, Clinical Impact and Interventions, Volume IIIView all 27 articles
Emerging SARS-CoV-2 Variants: Genomic Variations, Transmission, Pathogenesis, Clinical Impact, and Interventions Volume III
Provisionally accepted
- 1National Institute for One Health, Nagpur, Maharashtra, India
- 2Centers for Disease Control and Prevention (Georgia), Atlanta, Georgia
- 3ICMR-National Institute of Virology, Pune, India
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Public health strategies and vaccine effectiveness and therapeutic interventions continue to be affected by ongoing evolution of the SARS-CoV-2 through newly detected variants. Various research studies in this issue presents a complete perspective about new SARS-CoV-2 variants by investigating their genomic development and transmission patterns as well as immune evasion processes and clinical manifestations of emerging strains particularly analyzing Omicron subvariants. The editorial combines research insights from these studies into a cohesive presentation which fits within worldwide COVID-19 mitigation strategies.A clear comprehension of SARS-CoV-2 genetic evolution is required to track the capacity to evolve and spread. The study by Schnaubelt et al. shows efficiency of self-collected saliva specimens to achieve real-time genomic surveillance in occupational setting. The researchers discovered that Ct value optimization for sequencing referral creates an essential tool for detecting future infectious respiratory pathogen outbreaks (Schnaubelt et al.). This research validates decentralized testing methods as a suitable approach since they provide both accessible examination procedures for other respiratory pathogens alongside scalable and non-invasive testing methods. The current situation with SARS-CoV-2 variant emergence demands collaborative approach combining genomic surveillance methods and immunological research and clinical evaluation and public health implementation. This issue includes a comprehensive collection of research articles that describe major advances in the research on viral evolution and transmission and their clinical significance. These findings will help in developing preparedness strategies and optimizing interventions for evolving SARS-CoV-2 variants in future.
Keywords: Emerging SARS-CoV-2 variants, Genomic variations, Pathogenesis, Clinical impact, intervention
Received: 21 Apr 2025; Accepted: 28 Apr 2025.
Copyright: © 2025 Patil, Rodriguez and Yadav. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Pragya D Yadav, ICMR-National Institute of Virology, Pune, India
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