CASE REPORT article
Front. Med.
Sec. Nuclear Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1618256
This article is part of the Research TopicCase Reports in PET Imaging 2024View all 4 articles
Journal: FRONTIERS IN MEDICINE -SECTION NUCLEAR MEDICINE TITLE: "CASE REPORT: PITUITARY METASTASIS FROM PROSTATE ADENOCARCINOMA -AN INTEGRATED DIAGNOSIS VIA 68 Ga-PSMA PET/CT AND METHYLOME ANALYSIS"
Provisionally accepted
Nicola Bianchetto Wolf1
Ismini Charis Mainta1Aikaterini Fitsiori1Gina Colarusso1Petros Tsantoulis1Kristof Levente Egervari1Valentina Garibotto1,2*- 1University Hospitals of Geneva, Geneva, Switzerland
- 2University of Geneva, Geneva, Geneva, Switzerland
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Pituitary metastases are rare, accoun ng for only 1% of all pituitary tumor resec ons. Prostate adenocarcinoma, a common malignancy in men, seldom metastasizes to the pituitary gland, with only a few reported cases. Given their rarity and nonspecific clinical presenta on, pituitary metastases are o en mistaken for primary sellar lesions. Advanced imaging techniques, including Prostate-Specific Membrane An gen (PSMA) PET/CT, and molecular diagnos cs such as DNA methyla on profiling, can aid in accurate diagnosis and differen a on from pituitary adenomas.
Keywords: prostate cancer, Pituitary metastasis, PSMA PET/CT, MRI, DNA methyla on profiling
Received: 25 Apr 2025; Accepted: 30 May 2025.
Copyright: © 2025 Bianchetto Wolf, Mainta, Fitsiori, Colarusso, Tsantoulis, Egervari and Garibotto. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Valentina Garibotto, University Hospitals of Geneva, Geneva, Switzerland
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