CASE REPORT article
Front. Med.
Sec. Obstetrics and Gynecology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1620400
Occult heterotopic intramural ectopic pregnancy misdiagnosed by two-dimensional ultrasound: Two case reports
Provisionally accepted
- 1Zhejiang Hospital, Hangzhou, China
- 2Zhejiang Chinese Medical University, Hangzhou, China
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We report two cases of Heterotopic intramural ectopic pregnancy (HIMP) after multiple abortions, with lesions located near the uterine fundus or uterine horn, which is very difficult to diagnose by early two-dimensional transvaginal sonography (TVS). We analyzed multimodal images in combination with transabdominal ultrasound (TAS), color doppler flow imaging (CDFI), threedimensional TVS and magnetic resonance imaging (MRI) technology for early diagnosis and ultimately removed the gestational sac tissue via hysteroscopy. The combination of multimodal imaging techniques, serum β-hCG, and clinical vigilance should be considered to prevent catastrophic consequences of HIMP, especially when conventional two-dimensional TVS results are equivocal or misleading.
Keywords: Case description, ultrasound, Transvaginal sonography, Ectopic pregnancy, MRI
Received: 09 May 2025; Accepted: 11 Aug 2025.
Copyright: © 2025 Zhang, Dong, Guo, Ma and Bin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Huang Bin, Zhejiang Hospital, Hangzhou, China
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