REVIEW article
Front. Med.
Sec. Precision Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1621148
This article is part of the Research TopicInnovative Personalized Medicine Strategies for Managing Multi-MorbidityView all 11 articles
Personalized Peripheral Vascular Interventional 1 Embolization for Tumor: Tailoring Treatment to Improve Outcomes
Provisionally accepted
- The Third Affiliated Hospital of Gansu University of Chinese Medicine, Baiyin, China
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Malignant tumors pose a significant global health burden, necessitating innovative treatment 12 approaches. Personalized peripheral vascular interventional embolization emerges as a promising 13 strategy to enhance outcomes in tumor therapy. This review consolidates evidence on the principles, 14 influencing factors, implementation processes, and clinical applications of this approach. By analyzing 15 tumor vascular anatomy and biological behavior, along with patient-specific factors, clinicians can 16 tailor embolization techniques and materials to maximize efficacy and minimize complications. In 17 practical clinical settings, personalized embolization has shown remarkable potential to enhance 18 patient outcomes. For instance, in patients with hepatocellular carcinoma, personalized 19 chemoembolization not only significantly improved survival rates but also reduced post-procedure 20 complications, thereby improving quality of life. Similarly, in colorectal cancer liver metastases, the 21 combination of embolization with anti-angiogenic agents has proven effective in controlling disease 22 progression, offering a new therapeutic option where conventional treatments fall short. Clinical 23 studies have demonstrated the effectiveness of personalized embolization in improving survival rates 24 and quality of life for patients with various malignancies, including hepatocellular carcinoma and 25 colorectal cancer liver metastases. Despite challenges such as technical complexity and treatment costs, 26 advancements in imaging technology, genomics, and novel embolic agent development offer 27 substantial opportunities to refine and expand the application of personalized interventional 28 embolization, potentially transforming the landscape of cancer treatment.
Keywords: personalized medicine, tumor embolization, Interventional Oncology, Peripheral Vascular Disease, Drug-eluting beads, Tumor biology, therapeutic outcomes, Precision treatment
Received: 30 Apr 2025; Accepted: 15 Sep 2025.
Copyright: © 2025 Qi, Liu, Liu and Hao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Huaxin Hao, 17358186007@163.com
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