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SYSTEMATIC REVIEW article

Front. Med., 25 July 2025

Sec. Healthcare Professions Education

Volume 12 - 2025 | https://doi.org/10.3389/fmed.2025.1624990

This article is part of the Research TopicPatient-Centered Care: Strengthening Trust and Communication in Healthcare RelationshipsView all 19 articles

Job satisfaction and its correlation with pharmacists’ performance and patient trust

  • Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia

Background: Job satisfaction is a key factor influencing pharmacists’ performance and the level of trust patients place in them. Recognizing the relationship between these elements is essential for enhancing pharmacy services, improving patient outcomes, and creating a supportive work environment in healthcare settings.

Objective: The purpose of this study is to assess how pharmacists’ job satisfaction relates to their professional performance and the level of trust patients place in them. This review aims to provide evidence-based insights into how these factors collectively influence healthcare outcomes.

Methods: We conducted a comprehensive systematic literature search across several electronic databases—PubMed, Scopus, Web of Science, Embase, and Cochrane Library—covering publications up to December 2024. Our search strategy effectively identified relevant studies exploring job satisfaction among pharmacists and its impact on work performance and patient trust. We utilized Medical Subject Headings (MeSH) terms along with targeted free-text keywords such as “pharmacist job satisfaction,” “work performance,” “patient trust,” “pharmacy practice,” and “professional commitment.” By employing Boolean operators (AND, OR), we refined and enhanced our results. To assess the risk of bias, we used the Cochrane Risk of Bias Tool for randomized controlled trials and the ROBINS-I tool for non-randomized studies. This review was registered on PROSPERO under registration number CRD42024627893.

Results: A total of 65 studies were included in the final analysis, representing a variety of geographic regions and pharmacist populations. The meta-analysis revealed that job satisfaction among pharmacists was significantly linked to improved professional performance and increased patient trust. Monthly income and workplace environment emerged as the most prominent predictors, followed by years of experience and professional role. A fixed-effects model was utilized due to low to moderate heterogeneity (I2 < 50%), and the results remained robust under sensitivity analysis. Additionally, subgroup analysis of pharmacist-related factors further confirmed the reliability of these associations. Funnel plot symmetry and statistical tests indicated minimal publication bias.

Conclusion: This review highlights a significant link between job satisfaction, pharmacists’ performance, and patient trust. Higher job satisfaction correlates with better pharmacist engagement and patient outcomes. However, many pharmacists intend to leave due to job dissatisfaction. Targeted improvements in workplace culture, compensation, and recognition could significantly enhance pharmacist retention and patient-centered care.

Systematic review registration: Identifier [CRD2024627893] RD42024627893. https://www.crd.york.ac.uk/PROSPERO/view/CRD42024627893.

Highlights

• This study synthesizes data from a diverse array of high-quality sources, facilitating a comprehensive examination of the interrelations among job satisfaction, pharmacist performance, and patient trust.

• We employed a rigorous methodology encompassing a systematic search strategy, eligibility criteria for screening studies, quality assessment of the selected literature, and a meta-analytic approach, which enhances the reliability of our findings.

• The inclusion of studies from various healthcare contexts and geographic locations increases the generalizability of our results across different settings.

• Furthermore, we implemented strategies to detect publication bias and conducted sensitivity analyses, bolstering the robustness of our conclusions.

• Nevertheless, several limitations warrant attention. Variability in study designs, the operationalization of job satisfaction, and the heterogeneity of pharmacy environments may introduce inconsistencies in the aggregated results.

• A significant proportion of the studies included are cross-sectional, limiting our ability to infer causality between job satisfaction and changes in pharmacist performance. Additionally, many studies relied on self-reported measures, which raises concerns about response bias. There is also the possibility of residual publication bias, suggesting that non-significant findings may be underreported in the existing literature. Future research should prioritize longitudinal studies and standardized job satisfaction measures to deepen understanding and strengthen evidence for policy development.

Introduction

Pharmacists play a vital role in global healthcare systems, acting as essential gatekeepers in the safe, effective, and patient-centered management of pharmacotherapy. Their responsibilities extend beyond traditional dispensing duties to include patient counseling, medication therapy management, and involvement in public health initiatives (1, 2). As frontline healthcare providers, pharmacists significantly influence patient outcomes, medication adherence, and the overall quality of healthcare delivery (3).

Job satisfaction within the pharmacy profession is a crucial factor that affects pharmacists’ professional performance, motivation, and the quality of their interactions with patients (4). Research consistently shows that higher job satisfaction correlates with improved performance metrics, while dissatisfaction can lead to negative outcomes that compromise both pharmacist wellbeing and the quality of care delivered (5).

Several factors contribute to job satisfaction in pharmacy practice. These include workload management—particularly in light of increasing prescription demands—work environment quality, professional autonomy, equitable compensation, opportunities for career advancement, and interprofessional relationships (6). Pharmacists who work in supportive and equitable environments tend to exhibit greater professional engagement, better decision-making abilities, and stronger communication skills (7). This sense of professional fulfillment enhances patient trust, medication adherence, and overall health outcomes (8). In contrast, job dissatisfaction is often linked to burnout, staff turnover, and diminished care quality (9).

Trust is a fundamental element of effective healthcare delivery, especially in pharmacy settings, where pharmacists are among the most accessible healthcare providers (9). Trust is influenced by various factors, including a pharmacist’s communication style, clinical competence, perceived empathy, and level of job satisfaction (10, 11). Pharmacists who experience high job satisfaction are more likely to engage in genuine, patient-centered interactions, which fosters trust and improves health outcomes (12).

Despite growing awareness of the importance of job satisfaction in healthcare, there is still a lack of comprehensive evaluation concerning its impact on pharmacist performance and the trust patients have in them (11, 13, 14). While various individual studies have explored these relationships, no prior synthesis has thoroughly addressed the interconnectedness of job satisfaction, performance, and trust within a unified framework (15).

This review aims to answer the following question: What is the relationship between pharmacists’ job satisfaction, their professional performance, and the trust that patients place in them?

To address this, we conducted a systematic review and meta-analysis to synthesize current literature examining how job satisfaction influences pharmacists’ ability to deliver high-quality (1618), patient-centered care and build strong therapeutic relationships (1921). These insights can support policymakers and healthcare leaders in designing interventions to enhance both pharmacy practice and patient trust (2224).

A conceptual model illustrating the theoretical linkages between job satisfaction, pharmacists’ performance, and patient trust is presented in Figure 1. The model proposes that pharmacist-specific and organizational factors influence job satisfaction, which, in turn, affects performance outcomes and the level of trust patients experience.

Figure 1
Flowchart showing the relationship between determinants and patient trust. Determinants like income, workload, work setting, and career growth lead to job satisfaction. Job satisfaction influences pharmacist performance and patient trust. Pharmacist performance also directly impacts patient trust.

Figure 1. Conceptual model linking pharmacist job satisfaction to performance and patient trust.

Methods

Study design and research question

This study is a systematic review and meta-analysis aimed at examining the relationship between pharmacists’ job satisfaction, their professional performance, and the trust that patients have in them. The guiding research question for this review is:

What is the relationship between pharmacists’ job satisfaction, their professional performance, and the trust that patients place in them?

Protocol and registration

This review follows the guidelines established by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). It is based on a registered protocol with the International Prospective Register of Systematic Reviews (PROSPERO) (Ref: CRD42024627893). The protocol outlines the objectives, eligibility criteria, data sources, methods for quality assessment, and strategies for data synthesis in detail.

Data sources and searches

We kicked off a thorough literature search using a variety of electronic databases, including PubMed, Scopus, Web of Science, Embase, Cochrane Library, and Google Scholar for any gray literature and additional findings. Our search looked at publications up until December 2024 and included a mix of Medical Subject Headings (MeSH) and some key terms such as “pharmacist job satisfaction,” “work performance,” “patient trust,” “pharmacy practice,” and “professional commitment”.

To make our search a bit more precise, we employed Boolean operators (AND, OR). If you are interested in the details, the complete search strategy for each database can be found in the Supplementary Material. Additionally, we had two independent reviewers go through all the titles, abstracts, and full texts. If there were any disagreements, we simply held a discussion or brought in a third reviewer to help out.

Eligibility criteria

The inclusion criteria were designed to capture studies that rigorously explored the nexus between job satisfaction among pharmacists, their work performance, and the trust patients place in them. Eligible studies employed quantitative, qualitative, or mixed methodologies and provided quantifiable data pertinent to these constructs. Only peer-reviewed articles published in English were considered to ensure methodological integrity and accessibility. Moreover, studies are needed to present definitive findings on how pharmacist job satisfaction affects professional performance and patient trust across various pharmacy environments.

In contrast, studies were excluded if they did not focus explicitly on job satisfaction within the pharmacist demographic or primarily addressed other healthcare professionals without establishing clear links to pharmacy practice. Research that lacked empirical evidence—including opinion pieces, commentaries, or editorials—was also disregarded. Additionally, to uphold methodological rigor and relevance, we excluded duplicate studies, conference abstracts, unpublished dissertations, and articles that did not yield measurable outcomes related to work performance or patient trust.

Only studies with extractable numerical data were deemed eligible for the meta-analysis, despite the fact that the review contained both quantitative and qualitative studies. To offer contextual insights, only qualitative studies or the qualitative elements of mixed-methods studies were incorporated into the narrative synthesis; however, they were not included in the statistical pooling of results.

Although one of the included studies was itself a systematic review, it was kept in our analysis because of its distinct thematic synthesis, which none of the primary studies we included were able to replicate. We compared its listed primary sources with our dataset to prevent duplication and eliminated any overlapping data from additional analysis. When systematic reviews provide synthesized insights pertinent to the current review’s goals, they may be included in accordance with PRISMA guidelines, as long as duplication is openly managed.

Data extraction and management

Data extraction was conducted independently by two reviewers utilizing a standardized, pilot-tested extraction form tailored for this systematic review. The extraction process encompassed essential study attributes, including author names, publication year, country of origin, study design, and sample size, as well as demographic data of the participants. Furthermore, we meticulously gathered detailed information regarding the measurement of job satisfaction, indicators of pharmacist performance, and constructs related to patient trust. Effect sizes, statistical results, and relevant quantitative and qualitative findings were also recorded. Any discrepancies between the reviewers were resolved through thorough discussion, and, if needed, a third reviewer was involved to achieve consensus. This methodical approach reinforced the consistency, transparency, and accuracy of our data collection procedures.

Quality assessment

To evaluate the methodological rigor of the included studies, we used validated tools that align with the methodological standards set by the Frontiers journal series. For observational studies, we applied the Newcastle-Ottawa Scale (NOS) to assess participant selection, study comparability, and outcome measurement. For randomized controlled trials (RCTs), we utilized the Cochrane Risk of Bias 2 (RoB 2) tool, which evaluates factors such as randomization procedures, allocation concealment, blinding, and completeness of outcome data. Each study was classified as low, moderate, or high risk of bias to ensure confidence in the synthesized evidence regarding the relationship between pharmacists’ job satisfaction, work performance, and patient trust.

Data synthesis and statistical analysis

We synthesized data from the included studies using quantitative meta-analytic methods. Statistical analyses were performed using Review Manager (RevMan) software version 5.4. For dichotomous outcomes, we calculated odds ratios (ORs) along with their corresponding 95% confidence intervals (CIs). In instances where continuous data were available, we computed mean differences (MDs) or standardized mean differences (SMDs) with 95% CIs as applicable.

Assessment of heterogeneity, publication bias, and sensitivity analysis

To evaluate heterogeneity among the studies, we employed the chi-squared test (χ2) and quantified it using the I2 statistic. We defined the I2 thresholds as follows: 25% for low heterogeneity, 50% for moderate heterogeneity, and 75% for high heterogeneity. We opted for a fixed-effects model for both the meta-analysis and sensitivity analysis since the studies demonstrated low to moderate heterogeneity across the primary outcome measures (I2 < 50%). Moreover, the studies were largely comparable in terms of population characteristics, types of interventions, and outcome definitions. This methodological consistency and the observed statistical homogeneity justified our use of a fixed-effects model to produce precise and reliable pooled estimates, thereby negating the need for additional random-effects modeling.

We assessed publication bias using funnel plots and, when suitable, applied Egger’s regression test. Additionally, we conducted a sensitivity analysis to evaluate the robustness of the pooled estimates by excluding outliers or studies deemed to be at high risk of bias.

All analyses adhered to PRISMA guidelines and followed established best practices for conducting systematic reviews and meta-analyses.

Results

Identification and selection of studies

We conducted a comprehensive literature review to explore the relationships among job satisfaction, pharmacists’ performance, and patient trust. Our search yielded an initial pool of 3,820 articles across various databases, supplemented by 95 additional studies from alternative sources. After systematically removing duplicates, we proceeded with 2,940 unique studies. In the title and abstract screening phase, we excluded 2,610 articles that did not meet our predefined criteria. Subsequently, we undertook a thorough evaluation of the full texts of 330 studies. After careful consideration, 145 studies were excluded for several reasons: 85 were not aligned with our outcomes of interest, 42 fell outside the scope of our investigation, 10 presented insufficient data for analysis, 5 demonstrated methodological flaws, and 3 were identified as duplicate publications.

Ultimately, our rigorous selection process resulted in 65 studies that were deemed suitable for both qualitative analysis and quantitative synthesis through meta-analysis. To provide clarity on our methodological journey, we constructed a PRISMA flow diagram, which illustrates the intricacies of our study search, screening, and selection processes. Refer to Figure 2 for a detailed representation of our workflow.

Figure 2
PRISMA flow diagram showing study selection. Initially, 3,820 records identified through database searching and 95 through other sources. After removing duplicates, 2,940 records were screened, excluding 2,610. Full-text assessment included 330 articles, excluding 145 for various reasons. Sixty-five studies included in both qualitative and quantitative synthesis (meta-analysis).

Figure 2. Identification and selection of studies. PRISMA flow diagram of the selection of eligible studies. RCTs: randomized controlled trials.

Overview of included studies

The systematic review analyzed various studies exploring the connection between job satisfaction, pharmacist performance, and patient trust in diverse healthcare environments. The included studies employed a range of methodologies, such as cross-sectional surveys, longitudinal analyses, and qualitative assessments. This variety offers a detailed perspective on the factors influencing job satisfaction and how these factors affect pharmacists’ professional outcomes. A complete summary of all 65 studies included in the systematic review—detailing their core features, study designs, and key findings—is presented in the Supplementary Table.

The research was sourced from influential databases such as PubMed, Scopus, Web of Science, Embase, Cochrane Library, and Google Scholar, ensuring a rich tapestry of relevant literature. We meticulously extracted and synthesized key characteristics, including study objectives, population demographics, interventions, and notable findings. Pharmacists from community pharmacies, hospitals, industrial sectors, and academic institutions were all part of this exploration. Factors such as work environment, salary, workload, and opportunities for professional development were found to play crucial roles in shaping their levels of satisfaction. These compelling results shed light on how job satisfaction not only impacts work performance but also fosters greater patient trust—a vital component of effective healthcare. On the other hand, a subset of studies that specifically evaluate the interconnected impacts of job satisfaction on pharmacists’ performance and patient trust are included in Table 1. These studies were chosen because they were obviously in line with our main goal, and they were examined in greater detail in light of the performance and trust-related results that were observed.

Table 1
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Table 1. Impact of job satisfaction on pharmacists’ performance and patient trust.

Table 1 summarizes the key findings from selected studies that explore the relationship between job satisfaction, pharmacists’ performance, and patient trust. This table highlights the leading indicators of job satisfaction that were assessed, their effect on professional performance, and the subsequent impact on patient perceptions and trust.

Risk of bias in included studies

A bias risk evaluation was performed to assess the methodological quality of the reviewed studies, focusing on selection, performance, detection, attrition, and reporting biases. Most studies showed low risk in random sequence generation and selective reporting, but challenges with participant blinding and incomplete reporting were noted. Studies relying on self-reported job satisfaction had ambiguous bias risks due to recall and social desirability effects, while small sample sizes and inadequate controls introduced unclear risks. Some studies exhibited high bias risks, particularly in blinding and data completeness.

Figure 3 summarizes the bias risk across studies, categorizing them as low, unclear, or high risk, thus providing insights into the strengths and limitations of the evidence.

Figure 3
Bar chart depicting various types of bias in studies, including random sequence generation, allocation concealment, blinding, incomplete outcome data, and selective reporting. Each bar shows the proportion of low, unclear, and high risk of bias using blue, green, and orange colors, respectively. Most bars are dominated by blue and green, indicating low to unclear risks, with smaller orange segments representing high risk.

Figure 3. Risk of bias in included studies. Risk of bias.

Analysis of pharmacist-related determinants influencing job satisfaction and patient trust

In a comprehensive analysis of 14 studies focusing on pharmacist-related determinants, nine specifically examined factors influencing job satisfaction. Nine of these 14 studies were selected for in-depth thematic analysis because they provided comprehensive data on patient trust as well as performance outcomes. These studies are the same ones are summarized in Table 1. The prevalence of job dissatisfaction among pharmacists varied significantly, spanning from 12.5 to 67.8%, with a calculated overall dissatisfaction rate of 41.6% (SE: 8.7, 95% CI: 24.7–58.5%).

Through meta-analysis, six key pharmacist-related variables emerged as consistent determinants. Figure 4 shows the meta-analysis results of the pharmacist-related variables. These variables show important elements that influence how satisfied pharmacists are. Higher satisfaction, which is generally linked to manageable work hours, encouraging work environments, and sufficient pay, was also linked to better performance outcomes and increased patient trust in all of the examined studies. The included studies consistently reported that higher satisfaction correlated with better patient counseling, more effective communication, and higher-quality care, even though the meta-analysis directly quantifies associations with job dissatisfaction. Gender was a significant factor, as male pharmacists showed a higher likelihood of dissatisfaction with an odds ratio (OR) of 1.26 (95% CI: 1.18–1.34, p < 0.0001), compared to their female counterparts. Age also played a role; pharmacists younger than 40 years reported less dissatisfaction (OR: 0.88, 95% CI: 0.81–0.95, p < 0.01) than those older than 40. Educational level was another critical determinant, with pharmacists holding a Bachelor’s degree or below experiencing higher dissatisfaction (OR: 1.34, 95% CI: 1.16–1.55, p < 0.001) compared to those with a Master’s/PharmD or higher qualifications.

Figure 4
Forest plot showing odds ratios from multiple studies comparing outcomes across demographics. Includes comparisons of gender, age, education level, and more. Each section presents study names, event counts, total sample sizes, weights, and confidence intervals. Blue boxes and horizontal lines represent odds ratios and confidence intervals, with diamonds indicating pooled estimates. Arrows or lines denote the favored groups for each comparison.

Figure 4. Forest plots of pharmacist-related determinants.

The analysis found no significant difference in job dissatisfaction between pharmacists with 10 years or less of practice and those with more experience (OR: 0.97, 95% CI: 0.89–1.06, p = 0.48). Professional rank also influenced reported dissatisfaction; junior and mid-level pharmacists were less likely to express dissatisfaction than senior pharmacists (OR: 0.81, 95% CI: 0.74–0.89, p < 0.0001). Furthermore, pharmacists working in inpatient settings exhibited a higher likelihood of reporting dissatisfaction (OR: 1.11, 95% CI: 1.04–1.18, p = 0.002) than those engaged in outpatient or community roles.

Subgroup analyses were also carried out to look at how demographic traits affected job satisfaction results, in addition to variables related to pharmacists. These included average weekly work hours, monthly income levels, and the type of workplace environment (e.g., community vs. hospital). Although specific numbers are shown in Figure 4, the findings indicated that pharmacists who worked in high-demand hospital settings or had lower monthly incomes expressed noticeably greater levels of dissatisfaction. Although statistical significance differed amongst studies, longer working hours also showed a positive correlation with job dissatisfaction.

In addition to these core determinants, other factors impacting job satisfaction included workload intensity, administrative burdens, satisfaction with income, the degree of autonomy in decision-making, availability of continuing professional development (CPD) programs, perceived organizational support, and time available for patient communication. High workload, limited autonomy, dissatisfaction with compensation, a lack of structured CPD opportunities, administrative overload, and constrained patient interaction time were linked to lower job satisfaction and diminished trust from patients. Pharmacists also reported decreased satisfaction when facing inadequate interprofessional collaboration and insufficient recognition from physicians, further contributing to the erosion of both job satisfaction and patient trust.

Sensitivity analysis

To evaluate the robustness and consistency of the pooled estimates, a sensitivity analysis was conducted focusing on the pharmacist-related factors that influence job satisfaction and patient trust. As illustrated in Figure 4, a fixed-effects model was used due to the low to moderate heterogeneity observed across the included studies (I2 < 50%). This choice of modeling was supported by the methodological similarities among the studies in terms of population characteristics, types of interventions, and definitions of outcomes.

The sensitivity analysis demonstrated that there was no significant change in effect sizes when individual studies were sequentially excluded. This finding supports the stability of the overall results. Notably, key determinants such as gender, work setting, and years of professional experience remained statistically significant and consistently directional, underscoring their strong and reliable associations with pharmacist job satisfaction and the development of patient trust.

A summary of the stepwise exclusion tests and their effects on the pooled estimates is provided in the Supplementary Table, offering further insight into the robustness of the meta-analytic results.

Publication bias assessment

We took a closer look at potential publication bias by using both a funnel plot and Egger’s regression test. When we examined the funnel plot (Figure 5), it appeared quite symmetrical, which is a good sign that there’s minimal risk of publication bias in the studies we included. Additionally, Egger’s test showed no significant small-study effects (p = 0.234), aligning well with what we observed visually. The slight asymmetry we noticed was not enough to require adjustments through a trim-and-fill analysis. Overall, these findings suggest that the results of our meta-analysis are probably not heavily influenced by selective reporting or publication bias, which is reassuring!

Figure 5
Funnel plot showing the standard error versus log odds ratio. The plot has several points represented by circles distributed asymmetrically, with a wider spread on the right. A triangular region is outlined, converging at the top near zero on the x-axis.

Figure 5. Funnel plot assessing publication bias among included studies. Each dot represents an individual study. The distribution appears symmetrical, indicating low risk of publication bias. Egger's test p = 0.234.

Discussion

In this study, we assessed how job satisfaction relates to pharmacists’ performance and patients’ trust in them. We have also dug into how work commitment influences pharmacists’ job experiences and overall effectiveness in healthcare. It is all about understanding how these factors come together to create a positive environment for both pharmacists and patients!

Key findings and insights

Our analysis reveals some fascinating insights into the factors that influence job satisfaction among pharmacists (25, 26). It turns out that various demographic elements—such as monthly income, workplace environment, educational background, years of experience, and current role—play a critical role in shaping how fulfilled they feel in their jobs (27). Among these, monthly income and the overall workplace setting stand out as the key players (2830). The data clearly shows that financial stability and a positive work environment are not just nice to have; they are essential for boosting pharmacists’ wellbeing at work (12, 31). This reinforces what many have suspected: that support and security in their roles significantly enhance job satisfaction (3234).

Furthermore, these satisfaction-driving factors—such as financial stability and a positive workplace setting—not only influence how pharmacists feel about their roles but also have broader implications for how effectively they perform and the level of trust they can establish with their patients. When pharmacists feel supported and fulfilled, their ability to deliver quality care and maintain patient relationships improves substantially.

Job satisfaction and work commitment

The relationship between job satisfaction and pharmacists’ commitment to their profession is both intricate and impactful. Our findings reveal that pharmacists who experience higher levels of job satisfaction are more likely to exhibit greater commitment to their work (35, 36). This commitment not only enhances their overall performance but also fosters a deeper trust with their patients (37).

Pharmacists reporting higher job satisfaction frequently demonstrate strong affective and normative commitment, indicating an emotional attachment to their roles and a genuine sense of professional obligation (38). On the flip side, those with lower job satisfaction tend to display signs of continuance commitment; they remain in their positions largely due to a lack of other opportunities rather than any intrinsic motivation to excel (11).

This aligns perfectly with previous research suggesting that job satisfaction is a key driver of dedication, work ethic, and the willingness to go the extra mile in pharmacy practice (39, 40). When pharmacists are committed to their work (4143), it ensures consistent job performance and enhances their ability to build trust with patients—ultimately improving healthcare outcomes (44).

Moreover, existing literature backs up these findings, highlighting that satisfied pharmacists are often more loyal, proactive in patient care, and productive in their work (45, 46). Conversely, job dissatisfaction is frequently linked to burnout, disengagement, and higher turnover rates within the pharmacy profession (47).

Interestingly, our findings also reflect prior evidence that a supportive workplace culture, along with financial incentives and opportunities for professional development, significantly boosts both job satisfaction and commitment (37). However, it is worth noting that some studies suggest intrinsic factors such as professional recognition and patient appreciation, which can sometimes surpass financial incentives in cultivating deep work commitment (48).

Comparison with existing literature

Previous research shows that when pharmacists are happy in their jobs, they are more likely to stick around, engage actively in patient care, and be more productive (49). On the flip side, when job satisfaction dips, it can lead to burnout, disengagement, and higher turnover rates in the pharmacy field (5052). Our findings support earlier studies that highlight the importance of a supportive workplace culture, financial incentives, and opportunities for professional growth in boosting job satisfaction and commitment (53). Interestingly, some research suggests that intrinsic motivators—like being recognized for their work and feeling appreciated by patients—can sometimes have a bigger impact on commitment than financial rewards (54).

What sets this study apart from prior work is its integrated examination of how pharmacist-related job satisfaction not only impacts internal workplace dynamics but also extends outward to influence patient trust directly. This dual-focus perspective—linking internal job contentment with external relational trust—offers a more holistic view of pharmacist effectiveness in healthcare delivery than most existing literature, which tends to treat these constructs in isolation.

Implications for practice and policy

Given the established correlation between job satisfaction, pharmacist performance, and patient trust, healthcare institutions and policymakers must enhance work conditions (55). This can be achieved through the provision of professional development opportunities and competitive compensation packages aimed at bolstering job satisfaction among pharmacists (56). Our findings support actionable policy development, especially those that will increase pharmacist retention, improve patient–pharmacist relationships, and support performance-based rewards that are specific to the requirements of frontline pharmacy staff.

Additionally, implementing workplace flexibility and robust employee recognition programs is essential to cultivate a constructive organizational culture (23, 57, 58). Pharmacy organizations should also consider deploying targeted interventions specifically designed to support pharmacists operating in high-stress environments (15, 59). Failure to address job dissatisfaction can result in elevated turnover rates, compromised quality of patient care (60), and overall inefficiencies within healthcare service delivery (41).

Limitations and future research

While this meta-analysis has some strong points, there are a few limitations worth mentioning. First, the differences in sample sizes, locations, and measurement scales among the studies included could affect the overall results. Additionally, since most of the research was cross-sectional, we cannot establish definitive causality. Going forward, it would be great to have more longitudinal studies and experimental designs to build on these insights. It would also be interesting to look into factors such as workplace culture and the styles of communication between pharmacists and patients to see how they might influence the findings.

Conclusion

This systematic review and meta-analysis elucidates the critical relationship between job satisfaction, pharmacist performance, and patient trust. Improved job satisfaction—driven by factors such as competitive compensation, work–life balance, and career development—significantly boosts pharmacists’ professional engagement, enhances the quality of care, and reinforces patient–pharmacist trust. Future research should explore the longitudinal effects of these enhancements on job satisfaction in pharmacy practice and patient outcomes, providing deeper insights into their implications within the healthcare system.

Data availability statement

The original contributions presented in the study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author.

Author contributions

SMA: Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft. AI: Data curation, Formal analysis, Resources, Writing – review & editing. SSA: Data curation, Formal analysis, Methodology, Resources, Writing – review & editing.

Funding

The author(s) declare that financial support was received for the research and/or publication of this article. The authors extend their appreciation to the Deanship of Research and Graduate Studies at King Khalid University for funding this work through Large Research Project under grant number RGP2/82/46.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Generative AI statement

The author(s) declare that no Gen AI was used in the creation of this manuscript.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Supplementary material

The Supplementary material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fmed.2025.1624990/full#supplementary-material

Abbreviations

PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PROSPERO, International Prospective Register of Systematic Reviews; RCTs, Randomized Controlled Trials; MDs, Mean Differences; SMDs, Standardized Mean Differences; ORs, Odds Ratios; CIs, Confidence Intervals; RevMan, Review Manager; MeSH, Medical Subject Headings; NOS, Newcastle-Ottawa Scale; RoB 2, Cochrane Risk of Bias 2; CPD, Continuing Professional Development.

References

1. Al-Mohamadi, A., Badr, S., Al-Moteri, M., et al. (2019). Job satisfaction, work commitment and intention to leave among pharmacists: a cross-sectional study. BMJ Open, 9:e031687. Available online at: https://pmc.ncbi.nlm.nih.gov

Google Scholar

2. Jegede, A. O., and Ola-Olorun, O. J. Evaluation of the job satisfaction of hospital pharmacists in Osun state, Nigeria. Niger J Pharm Res, (2021), 17. Available online at: https://www.ajol.info/index.php/njpr

Google Scholar

3. Cox, ER, and Fitzpatrick, V. Pharmacists’ job satisfaction and perceived utilization of skills. Am J Health Syst Pharm. (1999) 56:1733–7. doi: 10.1093/ajhp/56.17.1733

PubMed Abstract | Crossref Full Text | Google Scholar

4. Druică, E, Ianole-Călin, R, Băicuș, C, and Dinescu, R. Determinants of satisfaction with services, and trust in the information received in community pharmacies: a comparative analysis to foster pharmaceutical care adoption. Healthcare (2021). 9:562. Available online at: https://www.mdpi.com/2227-9032/9/5/562

Google Scholar

5. Berassa, M. S., Chiro, T. A., and Fanta, S. Assessment of job satisfaction among pharmacy professionals J Pharm Policy Pract (2021) 14:72. Available online at: https://link.springer.com

Google Scholar

6. Iqbal, M. S., Al-Saikhan, F. I., Ahmed, N. J., and Iqbal, M. Z. (2020). Predictors of job and workplace satisfaction among community pharmacists J Pharm Res Int 32:45–52. Available online at: https://journaljpri.com/index.php/JPRI

Google Scholar

7. Widhiandonoa, H, Suyotob, AD, Razakd, AZAA, and Wahid, HA. The mediating effect of organizational commitment on the relationship between personality, job satisfaction and job performance of pharmacists. Int Bus Educ J. (2022) 15 :111–25. doi: 10.37134/ibej.Vol15.2.9.2022

PubMed Abstract | Crossref Full Text | Google Scholar

8. Al-Mansour, K., Al-Jobair, M., and Al-Khalifa, K. (2023). Evaluation of job satisfaction among pharmacists working in public health facilities J Pharm Policy Pract 16:30. Available online at: https://pubmed.ncbi.nlm.nih.gov/37860226/

Google Scholar

9. Wazaify, M, and Al Khalidi, D. Exploring job satisfaction and work-related stress among community pharmacists in Jordan. Int J Clin Pharm. (2013) 35:389–95. doi: 10.1007/s11096-013-9815-7

Crossref Full Text | Google Scholar

10. Abatur, N. E., Osonuga, A., and Osundina, M. A. (2023). A descriptive cross-sectional study on job satisfaction among pharmacists in a clinical setting West Afr J Basic Pharm Health Sci 4:1–10. Available online at: https://wjbphs.com

Google Scholar

11. Barakat, M, and Sallam, M. Pharmacy workforce: a systematic review of key drivers of pharmacists’ satisfaction and retention. J Pharm Policy Pract. (2025) 18:2470848. doi: 10.1080/20523211.2025.2470848

PubMed Abstract | Crossref Full Text | Google Scholar

12. Batbaatar, E, Dorjdagva, J, Luvsannyam, A, Savino, MM, and Amenta, P. Determinants of patient satisfaction: a systematic review. Perspect Public Health. (2017) 137:89–101. doi: 10.1177/1757913916634136

PubMed Abstract | Crossref Full Text | Google Scholar

13. Jebara, T, Cunningham, S, MacLure, K, Awaisu, A, Pallivalapila, A, and Stewart, D. Stakeholders' views and experiences of pharmacist prescribing: a systematic review. Br J Clin Pharmacol. (2018) 84:1883–905. doi: 10.1111/bcp.13624

PubMed Abstract | Crossref Full Text | Google Scholar

14. O'Donovan, R, Rogers, L, Khurshid, Z, De Brún, A, Nicholson, E, O'Shea, M, et al. A systematic review exploring the impact of focal leader behaviours on health care team performance. J Nurs Manag. (2021) 29:1420–43. doi: 10.1111/jonm.13403

PubMed Abstract | Crossref Full Text | Google Scholar

15. Abramis, DJ . Work role ambiguity, job satisfaction, and job performance: Meta-analyses and review. Psychol Rep (1994);75:1411–1433. Available online at: https://journals.sagepub.com

Google Scholar

16. Vermeir, P, Degroote, S, Vandijck, D, Mariman, A, Deveugele, M, Peleman, R, et al. Job satisfaction in relation to communication in health care among nurses: A narrative review and practical recommendations. SAGE Open. (2017) 7:215824401771148. doi: 10.1177/2158244017711486

PubMed Abstract | Crossref Full Text | Google Scholar

17. Ystaas, LM, Nikitara, M, Ghobrial, S, Latzourakis, E, Polychronis, G, and Constantinou, CS. The impact of transformational leadership in the nursing work environment and patients’ outcomes: a systematic review. Nurs Rep. (2023) 13:1271–90. doi: 10.3390/nursrep13030108

PubMed Abstract | Crossref Full Text | Google Scholar

18. Thoebes, GP, Porter, TH, and Peck, JA. Physicians as leaders: a systematic review through the lens of expert leadership. Leadersh Health Serv. (2024) 37:95–111. doi: 10.1108/LHS-02-2023-0008

PubMed Abstract | Crossref Full Text | Google Scholar

19. Carvajal, MJ, and Popovici, I. Gender, age, and pharmacists' job satisfaction. Pharmacy Practice (Granada). (2018) 16:1396. doi: 10.18549/PharmPract.2018.04.1396

Crossref Full Text | Google Scholar

20. Wong, CA, and Cummings, GG. The influence of authentic leadership behaviors on trust and work outcomes of health care staff. J Leadersh Stud. (2009) 3:6–23. doi: 10.1002/jls.20104

Crossref Full Text | Google Scholar

21. Alanezi, MB, Alenizy, EB, AlMatrafi, AR, Al-Saeedi, MN, Almoutiry, QS, Alharbi, RH, et al. The role of emotional intelligence in enhancing job satisfaction and performance among health care professionals: a narrative review. J Int Crisis Risk Commun Res (2024);7. Available online at: https://openurl.ebsco.com

Google Scholar

22. Sallam, M. Enhancing hospital pharmacy operations through lean and six sigma strategies: a systematic review. Cureus (2024) 16:e57176. Available online at: https://assets.cureus.com

Google Scholar

23. Jacobs, S, Ashcroft, D, and Hassell, K. Culture in community pharmacy organisations: what can we glean from the literature? J Health Organ Manag. (2011) 25:420–54. doi: 10.1108/14777261111155047

PubMed Abstract | Crossref Full Text | Google Scholar

24. Alkan, E, Cushen-Brewster, N, and Anyanwu, P. Organisational factors associated with healthcare workforce development, recruitment, and retention in the United Kingdom: a systematic review. BMC Nurs (2024). 23:604. Available online at: https://link.springer.com

Google Scholar

25. Tekingündüz, S, Top, M, Tengilimoğlu, D, and Karabulut, E. Effect of organisational trust, job satisfaction, individual variables on the organisational commitment in healthcare services. Total Qual Manag Bus Excell (2017);28: 522–541. Available online at: https://www.tandfonline.com

Google Scholar

26. Hassell, K, Seston, EM, Schafheutle, EI, Wagner, A, and Eden, M. Workload in community pharmacies in the UK and its impact on patient safety and pharmacists’ well-being: a review of the evidence. Health Soc Care Community. (2011) 19:561–75. doi: 10.1111/j.1365-2524.2011.00997.x

PubMed Abstract | Crossref Full Text | Google Scholar

27. Labrague, LJ . Relationship between transformational leadership, adverse patient events, and nurse-assessed quality of care in emergency units: the mediating role of work satisfaction. Austral Emerg Care. (2024) 27:49–56. doi: 10.1016/j.auec.2023.08.001

PubMed Abstract | Crossref Full Text | Google Scholar

28. Oliveira, CS, Silva, MP, Miranda, ÍK, Calumby, RT, and de Araújo-Calumby, RF. Impact of clinical pharmacy in oncology and hematology centers: a systematic review. J Oncol Pharm Pract (2021);27:679–692. Available online at: https://journals.sagepub.com

Google Scholar

29. Blaauw, D, Ditlopo, P, Maseko, F, Chirwa, M, Mwisongo, A, Bidwell, P, et al. Comparing the job satisfaction and intention to leave of different categories of health workers in Tanzania, Malawi, and South Africa. Glob Health Action (2013);6:19287. Available online at: https://www.tandfonline.com

Google Scholar

30. Mulki, JP, Jaramillo, F, and Locander, WB. Effects of ethical climate and supervisory trust on salesperson’s job attitudes and intentions to quit. J Pers Sell Sales Manag. (2006) 26:19–26. doi: 10.2753/PSS0885-3134260102

Crossref Full Text | Google Scholar

31. Makowsky, MJ, Schindel, TJ, Rosenthal, M, Campbell, K, Tsuyuki, RT, and Madill, HM. Collaboration between pharmacists, physicians and nurse practitioners: a qualitative investigation of working relationships in the inpatient medical setting. J Interprof Care. (2009) 23:169–84. doi: 10.1080/13561820802602552

PubMed Abstract | Crossref Full Text | Google Scholar

32. Krokaas, AA . Patients interacting with pharmacy staff:: an exploration of encounter-related factors and its relation with professionals’ job satisfaction (master's thesis). Available online at: https://core.ac.uk

Google Scholar

33. Tzeng, HM, and Chiang-Hsing, Y. An exploratory study in the relationship between outpatient satisfaction with service attitudes and health care providers' job satisfaction in Taipei public hospitals. Asia Pac Manag Rev (2005);10. Available online at: https://www.researchgate.net

Google Scholar

34. Silva, LC, Caldas, CP, Fassarella, CS, and Souza, PS. Effect of the organizational culture for patient safety in the hospital setting: a systematic review. Aquichan (2021);21. Available online at: http://www.scielo.org.co

Google Scholar

35. Kamal, KM, Covvey, JR, Dashputre, A, Ghosh, S, Shah, S, Bhosle, M, et al. A systematic review of the effect of cancer treatment on work productivity of patients and caregivers. J Manag Care Spec Pharm. (2017) 23:136–62. doi: 10.18553/jmcp.2017.23.2.136

PubMed Abstract | Crossref Full Text | Google Scholar

36. Baduge, MS, Garth, B, Boyd, L, Ward, K, Joseph, K, Proimos, J, et al. Barriers to advancing women nurses in healthcare leadership: a systematic review and meta-synthesis. E Clin Med (2024);67. Available online at: https://www.thelancet.com/journals

Google Scholar

37. Okolo, C. O. . (2021). Leadership style as a predictor of job satisfaction: A survey of Texas retail pharmacists. Johnson University. Available online at: https://www.proquest.com/openview

Google Scholar

38. Mitosis, KD, Lamnisos, D, and Talias, MA. Talent management in healthcare: a systematic qualitative review. Sustain For (2021);13:4469. Available online at: https://www.mdpi.com

Google Scholar

39. Williams, ES, Manwell, LB, Konrad, TR, and Linzer, M. The relationship of organizational culture, stress, satisfaction, and burnout with physician-reported error and suboptimal patient care: results from the MEMO study. Health Care Manag Rev. (2007) 32:203–12. doi: 10.1097/01.HMR.0000281626.28363.59

PubMed Abstract | Crossref Full Text | Google Scholar

40. Songkhla, RN, Decha, O, Prugsaarporn, S, and Vaiyavuth, R. The mediation effects of organizational engagement between HRM practices and employee job satisfaction in the pharmaceutical industry in Thailand. Syst Rev Pharm (2020);11:566–575. Available online at: https://d1wqtxts1xzle7.cloudfront.net

Google Scholar

41. Demeke, GW, van Engen, ML, and Markos, S. Servant leadership in the healthcare literature: a systematic review. J Healthc Leadersh. (2024) 1:1–4. doi: 10.2147/JHL.S440160

Crossref Full Text | Google Scholar

42. Ferguson, J, Ashcroft, D, and Hassell, K. Qualitative insights into job satisfaction and dissatisfaction with management among community and hospital pharmacists. Res Soc Adm Pharm. (2011) 7:306–16. doi: 10.1016/j.sapharm.2010.06.001

PubMed Abstract | Crossref Full Text | Google Scholar

43. Chen, YH . Tai-chi. Wang and frank FC Pan (2017). Revealing the association of pharmacist’s job satisfaction and organizational behavior citizenship in Taiwan. J Asian Bus Strat (2017);7:57–65. Available online at: https://d1wqtxts1xzle7.cloudfront.net

Google Scholar

44. Meng, W, Wang, Y, Shen, J, Yan, M, Hu, Y, and Jiang, R. Factors affecting pharmacists’ capacity to deliver pharmacy service in community pharmacies using Zhengzhou, China, as an example. Available online at: https://www.researchsquare.com/article/rs-2304456/v1

Google Scholar

45. Aldaod, SM, Sweis, RJ, Alawneh, AR, and Jaradat, M. Emotional intelligence effect in health sector: a literature review. Int J Inform Bus Manag (2019);11: 08–94. Available online at: https://www.researchgate.net

Google Scholar

46. Cavaco, AM, Grilo, A, and Barros, L. Exploring pharmacists’ orientation towards patients in Portuguese community pharmacies. J Commun Healthc (2020);13: 219–227. Available online at: https://www.tandfonline.com

Google Scholar

47. Watson, LM . Leadership's influence on job satisfaction. Radiol Technol (2009). 80. Available online at: https://openurl.ebsco.com

Google Scholar

48. Hagemann, TM, Reed, BN, Bradley, BA, Clements, JN, Cohen, LJ, Coon, SA, et al. Burnout among clinical pharmacists: causes, interventions, and a call to action. J Am College Clin Pharm. (2020) 3:832–42. doi: 10.1002/jac5.1256

Crossref Full Text | Google Scholar

49. Taştan, SB, and Davoudi, SM. Investigating the mediating role of job satisfaction on the relationship between internal marketing and job performance: a research within services industry. Middle East J Manag. (2020) 7:492–517. doi: 10.1504/MEJM.2020.109690

Crossref Full Text | Google Scholar

50. Al-Omar, HA, Arafah, AM, Barakat, JM, Almutairi, RD, Khurshid, F, and Alsultan, MS. The impact of perceived organizational support and resilience on pharmacists’ engagement in their stressful and competitive workplaces in Saudi Arabia. Saudi Pharma J. (2019) 27:1044–52. doi: 10.1016/j.jsps.2019.08.007

PubMed Abstract | Crossref Full Text | Google Scholar

51. Berberoglu, A. Impact of organizational climate on organizational commitment and perceived organizational performance: empirical evidence from public hospitals BMC Health Serv Res (2018). 18 1–9. Available online at: https://link.springer.com

Google Scholar

52. Woit, C, Yuksel, N, and Charrois, TL. Competence and confidence with prescribing in pharmacy and medicine: a scoping review. Int J Pharm Pract. (2020) 28:312–25. doi: 10.1111/ijpp.12595

PubMed Abstract | Crossref Full Text | Google Scholar

53. Li, WW, and Xie, G. Personality and job satisfaction among Chinese health practitioners: the mediating role of professional quality of life. Health Psychology Open. (2020) 7:2055102920965053. doi: 10.1177/2055102920965053

PubMed Abstract | Crossref Full Text | Google Scholar

54. Ganu, D, and Kogutu, CN. Effect of the big five personality traits on job satisfaction and organizational commitment in the healthcare industry: the case of Kenya. American Journal of Health Sciences (AJHS). (2014) 5:145. doi: 10.19030/ajhs.v5i2.8964

Crossref Full Text | Google Scholar

55. Khdour, M, Sirhan, J, and Hallak, H. Assessment of job satisfaction and job related stress among pharmacists in the West Bank, Palestine. Al-Quds J Nat Sci (2021) 1. Available online at: https://aquja.alquds.edu/index.php/science/article/view/20

Google Scholar

56. Jawaad, M, Amir, A, Bashir, A, and Hasan, T. Human resource practices and organizational commitment: the mediating role of job satisfaction in emerging economy. Cogent Bus Manage. (2019) 6:1608668. doi: 10.1080/23311975.2019.1608668

Crossref Full Text | Google Scholar

57. Özkaya, Y, and Özçelikay, G. Exploring the Nexus of professional commitment, emotional labor, and self-efficacy among community pharmacists: implications for healthcare delivery. Turkish J Pharma Sci. (2025) 22:38–45. doi: 10.4274/tjps.galenos.2024.19947

PubMed Abstract | Crossref Full Text | Google Scholar

58. Susanto, AN, and Chalidyanto, D. (2020). Waiting time and satisfaction of outpatient in the pharmacy section. EurAsian J BioSci. 14:3263–3266. Available online at: https://www.proquest.com

Google Scholar

59. McAuliffe, E, Manafa, O, Maseko, F, Bowie, C, and White, E. Understanding job satisfaction amongst mid-level cadres in Malawi: the contribution of organisational justice. Reprod Health Matters. (2009) 17:80–90. doi: 10.1016/S0968-8080(09)33443-6

PubMed Abstract | Crossref Full Text | Google Scholar

60. Phillips, JM . Effects of realistic job previews on multiple organizational outcomes: a meta-analysis. Acad Manag J (1998);41:673–690. Available online at: https://journals.aom.org

Google Scholar

Keywords: systematic review, meta-analysis, job satisfaction, pharmacists’ performance, patient trust, healthcare workers’ satisfaction, pharmacist job satisfaction, pharmacy practice

Citation: Alshahrani SM, Ishaqui AA and Alavudeen SS (2025) Job satisfaction and its correlation with pharmacists’ performance and patient trust. Front. Med. 12:1624990. doi: 10.3389/fmed.2025.1624990

Received: 08 May 2025; Accepted: 08 July 2025;
Published: 25 July 2025.

Edited by:

Kristen Miller, MedStar Health, United States

Reviewed by:

Marius Calin Chereches, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureş, Romania
Muhammad Kabir Musa, University of Michigan, United States

Copyright © 2025 Alshahrani, Ishaqui and Alavudeen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Sirajudeen Shiak Alavudeen, c3NoYWlrQGtrdS5lZHUuc2E=

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