SYSTEMATIC REVIEW article
Front. Med.
Sec. Regulatory Science
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1630272
This article is part of the Research TopicDissemination and Implementation Science in MedicineView all 7 articles
Summary of the Best Evidence for the Use of Antiseptics at Various Surgical Sites to Prevent Postoperative Infections
Provisionally accepted
- 1Shanghai Children's Hospital, shanghai, China
- 2School of Medicine, Tongji University, Shanghai, China
- 3Oriental Hospital Affiliated with Tongji University, Shanghai, China
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Objective: To retrieve and summarize the best available evidence regarding the use of antiseptics at various surgical sites to prevent postoperative infections.Methods: Following the "6S" evidence model, a comprehensive search was conducted across guideline repositories, professional association websites, and both Chinese and English databases. The search covered literature from database inception through December 2024. Two researchers trained in evidence-based nursing independently screened the literature, assessed quality, extracted data, and synthesized the findings.Results: A total of 30 studies met the inclusion criteria, consisting of 3 clinical decision support documents, 5 guidelines, 4 expert consensuses, 9 systematic reviews, and 9 evidence summaries. In total, 36 pieces of evidence were integrated across five key areas: general principles, recommended antiseptics for specific surgical sites, application methods, handling of special circumstances, and quality control.This study compiles the best current evidence on antiseptic use across different surgical sites for preventing postoperative infections. It lays a foundation for standardizing disinfection protocols and improving infection control in clinical practice. Healthcare professionals are encouraged to integrate this evidence with individual patient conditions and clinical judgment.
Keywords: Surgical site infection, Antiseptics, Evidence-Based Nursing, Best evidence, review - systematic
Received: 17 May 2025; Accepted: 29 Jul 2025.
Copyright: © 2025 Du, Wu, Jin and Ni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Li Ni, Oriental Hospital Affiliated with Tongji University, Shanghai, China
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