CASE REPORT article
Front. Med.
Sec. Nuclear Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1642218
This article is part of the Research TopicCase Reports in PET Imaging 2024View all 8 articles
18F-FDG PET/CT revealed small bowel metastasis from large cell lung carcinoma after treatment improvement: a case report
Provisionally accepted
- Affiliated Hospital of Zunyi Medical University, Zunyi, China
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Large cell lung carcinoma (LCLC) is a highly aggressive form of non-small cell lung cancer that frequently metastasizes to the brain, liver, bone, adrenal gland, and lymph nodes. Gastrointestinal metastasis, particularly to the small bowel, is relatively uncommon. Herein, we present a case of a patient with LCLC who developed abdominal pain 3 years after initial treatment response. Abdominal computed tomography (CT) and fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT imaging revealed a small bowel lesion, which was subsequently confirmed as metastatic disease from LCLC via pathological examination. As with our case highlights that, although small bowel metastases are rare in LCLC, they should be considered as a differential diagnosis in patients with LCLC who present gastrointestinal symptoms such as abdominal pain, bloating, or hematochezia following treatment.
Keywords: PET/CT, Large cell lung carcinoma, Small bowel metastasis, 18F-FDG, lung cancer
Received: 06 Jun 2025; Accepted: 25 Aug 2025.
Copyright: © 2025 Jiang, Li, Wen and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xianwen Hu, Affiliated Hospital of Zunyi Medical University, Zunyi, China
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