ORIGINAL RESEARCH article
Front. Med.
Sec. Geriatric Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1643181
Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fracture from Qatar
Provisionally accepted
Shirmila Syamala1*
Francisco Tarazona-Santabalbina²˒³2,3Jorge Luis Passarelli¹1
Brijesh Sathian1Navas Nadukkandiyil¹1Hanadi Alhamad¹1- 1Hamad Medical Corporation, Doha, Qatar
- 2Hospital La Ribera, Alzira, Spain
- 3Universidad Catolica de Valencia San Vicente Martir, Godella, Spain
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Background: Studies conducted in Western populations have shown that Clinical Frailty Scale is a major predictor of adverse outcomes in older hip fracture patients; however, there are no data from Middle Eastern populations, who may be culturally and ethnically different. We examined the association between preoperative Clinical Frailty Scale and multiple adverse outcomes in a cohort of patients with hip fractures (60-96 years) from Qatar.Methods: This prospective, single-center observational cohort study included 155 hip fracture patients aged ≥60 years from Qatar who underwent Clinical Frailty Scale assessment at baseline and were followed up for four outcomes of interest: incident delirium, postoperative complications, one-year all-cause mortality, and increased length of stay (length of stay ≥14 days).Results: One hundred and fifty-five patients with hip fractures (average age 74.6 years, 46.5% women) were included in the study. At baseline, 72.2% had a Clinical Frailty Scale score of <5, 12.3% had a score of 5, and 15.5% had scores >5. Higher baseline Clinical Frailty Scale categories were strongly and posi vely associated with delirium, postopera ve complica ons, and all-cause mortality, but not with length of hospital stay. Compared to Clinical Frailty Scale scores <5, the mul variable risk ra o [RR] (95% confidence interval [CI]) for those with scores >5 was 7.76 (3.17-18.97) for delirium, 3.59 (1.20-10.77) for postoperative complications, 6.39 (1.45-28.20) for all-cause mortality, and 1.43 (0.75-2.73) for length of stay ≥14 days.Clinical Frailty Scale was posi vely associated with delirium, postopera ve complica ons, and all-cause mortality but not with length of hospital stay in pa ents with hip fractures from Qatar.
Keywords: Frailty, Clinical Frailty Scale, Delirium, Mortality, Qatar, Middle-East
Received: 08 Jun 2025; Accepted: 09 Jul 2025.
Copyright: © 2025 Syamala, Tarazona-Santabalbina²˒³, Passarelli¹, Sathian, Nadukkandiyil¹ and Alhamad¹. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Shirmila Syamala, Hamad Medical Corporation, Doha, Qatar
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