ORIGINAL RESEARCH article
Front. Med.
Sec. Geriatric Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1644170
Correlation between metabolic syndrome indicators and locomotive syndrome in Chinese geriatric oncology inpatients
Provisionally accepted
- Affiliated Hospital of Jiangnan University, Wuxi, China
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Objective: To investigate the correlation between metabolic syndrome (MS) indicators and locomotive syndrome (LS) in geriatric oncology inpatients. Methods: This study enrolled 430 geriatric oncology inpatients at risk of LS, admitted to the Department of Oncology at Affiliated Hospital of Jiangnan University from January 2024 and December 2024. Waist circumference, diastolic blood pressure, systolic blood pressure, total cholesterol (TC), triacylglycerols (TG), fasting glucose, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured as MS indicators. The Geriatric Locomotive Function Scale (GLFS-25) was used to assess LS. Subjects were classified into two groups: those with LS (322 cases) and those without (87 cases), to analyze the correlation between MS indicators and LS. Results: 409 geriatric oncology inpatients completed the study. One-way linear regression analysis revealed that waist circumference, systolic blood pressure, diastolic blood pressure, TG, and LDL-C were positively correlated with GLFS-25 (P<0.05), while HDL-C was negatively correlated in geriatric oncology inpatients(P<0.05). Logistic regression analysis identified waist, systolic blood pressure, TG, and LDL-C as risk factors for developing LS in geriatric oncology inpatients (P< 0.05). Conclusion: Certain risk factors for MS are associated with increased GLFS-25 scores and the development of LS in geriatric oncology inpatients. Screening for LS is beneficial for the early diagnosis of MS and using LS as a focal point for intervention offers new insights into the comprehensive rehabilitation of geriatric oncology patients.
Keywords: Locomotive syndrome, metabolic syndrome, Aging, Geriatric oncology inpatients, Correlation
Received: 10 Jun 2025; Accepted: 25 Aug 2025.
Copyright: © 2025 Song, Jing, Li, Yang, Chen, Wu, Chen, Yu and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Rui-Rong Wu, Affiliated Hospital of Jiangnan University, Wuxi, China
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