Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Med.

Sec. Precision Medicine

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1653201

Prognostic Assessment and Intelligent Prediction System for Breast Reduction Surgery Using Improved Swarm Intelligence Optimization

Provisionally accepted
Zhiwei  CuiZhiwei CuiZhen  LiangZhen LiangChaohua  LiuChaohua LiuYongjun  ChenYongjun ChenNa  WangNa WangLIU  BINGYANGLIU BINGYANGLei  GuoLei GuoBaoqiang  SongBaoqiang Song*
  • Department of neurology, xijing hospital, Airforce military medical university, Xi'an, China

The final, formatted version of the article will be published soon.

=Objective: This study aimed to enhance the accuracy of prognosis assessment for reduction mammaplasty by improving a swarm intelligence optimization algorithm and to develop an intelligent prediction system to support clinical decision-making. Methods: This study enrolled 224 patients who underwent reduction mammaplasty at Xijing Hospital between January 14, 2018, and February 4, 2023, and 137 patients who underwent the same procedure at Plastic Surgery Hospital between January 14, 2018, and May 1, 2020, constituting the training set. Ninety-two patients who underwent reduction mammaplasty at Plastic Surgery Hospital between May 2, 2020, and February 4, 2023, were defined as the test set. Data collection encompassed preoperative anatomical parameters, intraoperative procedural characteristics, and postoperative follow-up outcomes. Prognostic indicators included postoperative complications and the BRQS score. Guided by the Improved Secretary Bird Optimization Algorithm (ISBOA), the optimization algorithm was integrated with an AutoML framework to achieve fully automated optimization spanning from feature selection to model parameter configuration. A classification model was employed to predict the occurrence of postoperative complications, while a regression model was used to predict patient satisfaction at one year postoperatively. Results: The ISBOA algorithm significantly outperformed other algorithms in stability, convergence speed, and avoidance of local optima. The AutoML framework achieved an ROC-AUC of 0.9369 and a PR-AUC of 0.8856 for complication prediction (test set), and an R² of 0.9165 for quality-of-life prediction (test set). SHAP analysis identified key features influencing complications and quality of life. Decision Curve Analysis (DCA) demonstrated that the AutoML model possessed high net benefit and stability across various threshold probabilities. The developed clinical decision support system could rapidly generate prediction results, aiding physicians in formulating personalized treatment plans. Conclusion: This study successfully constructed a prognosis assessment and intelligent prediction system for reduction mammaplasty based on an improved swarm intelligence optimization algorithm. The results indicate that the ISBOA algorithm exhibits significant advantages in global optimization performance and convergence efficiency. The AutoML model demonstrated excellent performance in predicting complications and assessing quality of life, with its clinical utility further validated by DCA.

Keywords: Breast reduction surgery, Improved swarm intelligence optimization algorithm, AutoML, Postoperative complication prediction, quality of life assessment, Intelligent prediction system, Clinical decision support

Received: 25 Jun 2025; Accepted: 25 Aug 2025.

Copyright: © 2025 Cui, Liang, Liu, Chen, Wang, BINGYANG, Guo and Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Baoqiang Song, Department of neurology, xijing hospital, Airforce military medical university, Xi'an, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.