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CASE REPORT article

Front. Med.

Sec. Translational Medicine

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1656640

Digit Salvage Therapy with Integrated Chinese and Western Medicine: Report of Case Series

Provisionally accepted
Jiaming  CuiJiaming Cui1Hanbo  WangHanbo Wang2Yanlong  YaoYanlong Yao3Junwei  ZongJunwei Zong4Ying  GongYing Gong4Ran  SunRan Sun4*Mingzhi  SongMingzhi Song5*
  • 1Affiliated Hospital of Nantong University, Nantong, China
  • 2Stony Brook University, Stony Brook, United States
  • 3Dalian Fourth People's Hospital, Dalian, China
  • 4The First Affiliated Hospital of Dalian Medical University, Dalian, China
  • 5Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

The final, formatted version of the article will be published soon.

Background Finger or toe trauma is a common orthopedic disease. However, the digit salvage treatment method for patients with severe tissue necrosis or infection is very effective. Methods Five retrospective cases with typical lesions received our integrated traditional Chinese and Western medicine digit salvage therapy. These cases were with necrosis and defect or osteomyelitis. According to the patient's different lesion characteristics, we carried out the integrated treatment of traditional Chinese and Western medicine with nibbling debridement, negative pressure wound treatment (NPWT), moisture burn ointment (MEBO), rehabilitation exercise and common surgical techniques. Results We considered that percarious alive tissue (PAT) in the residual tissue of the lesion area was very important, especially for promoting tissue regeneration and repairing defects. By nibbling debridement, PAT can be accurately identified. NPWT could protect wound, control infection and fully absorpt the effusion. MEBO was used for dressing changes. While rehabilitation exercise is very important to promote the function recovery. Additionally, bone drilling, skin-grafting and brace fixation were also used in different cases. The affected finger or toe healed completely during 1.5-18 months. All patients restored the movement function of the adjacent joints in the lesion area. There was no recurrence of infection or complaint of pain. Conclusion Therefore, traditional Chinese and Western medicine digit salvage therapy may offer an alternative to amputation in select cases. However, further research with larger sample sizes and controlled trials are still needed before wide application of this therapy.

Keywords: Digit salvage therapy, Tissue necrosis defect, Integrated Chinese and Western medicine, Npwt, Mebo

Received: 30 Jun 2025; Accepted: 16 Sep 2025.

Copyright: © 2025 Cui, Wang, Yao, Zong, Gong, Sun and Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Ran Sun, ranran-no.1@163.com
Mingzhi Song, songmingzhi@sjtu.edu.cn

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