CASE REPORT article
Front. Med.
Sec. Pulmonary Medicine
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1660190
This article is part of the Research TopicCase Reports in Pulmonary Medicine 2025View all 10 articles
Diagnosis and Treatment of Pulmonary Aspergillus Infection Secondary to Empyema Complicated with Lung Cancer: A Case Report
Provisionally accepted
- Yantai Yuhuangding Hospital, Yantai, China
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Background: This study aimed to explore the clinical characteristics, diagnosis, and management of iInvasive pPulmonary aAspergillosis (IPA) complicating empyema in a patient with lung cancer.We analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, including anti-infective and anti-tumor treatments, in a patient diagnosed with IPA-associated empyema and lung cancer. Histopathological examination of bronchoscopic biopsy specimens confirmed pulmonary adenocarcinoma, while bronchoalveolar lavage fluid cultures identified Aspergillus fumigatus. Following the development of secondary empyema, comprehensive anti-infective and anti-tumor therapies were administered, leading to disease control.IPA-associated empyema complicating lung cancer represents a rare clinical scenario.In patients presenting with IPA, the potential coexistence of lung cancer should be considered. An integrated approach combining antifungal therapy and active anti-tumor treatment is essential for managing such cases.
Keywords: lung cancer, Empyema, BALF, Bronchoscopic, Invasive pulmonary aspergillosis (IPA)
Received: 05 Jul 2025; Accepted: 31 Jul 2025.
Copyright: © 2025 Zhu, Liu, Gu, Shen and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yu yao Shen, Yantai Yuhuangding Hospital, Yantai, China
Ting shu Jiang, Yantai Yuhuangding Hospital, Yantai, China
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