ORIGINAL RESEARCH article
Front. Med.
Sec. Gastroenterology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1660818
This article is part of the Research TopicOpinions in Biliary and Pancreatic Diseases: 2025View all articles
Assessing the Impact of Enteral Nutrition on Peripancreatic Exudate in Acute Pancreatitis Using CT Volume Measurement
Provisionally accepted
Cui Hu1
Chengcheng Tian1Chen Chen2Mengxue Huang3Jun Li1Xin Gao1Dandan Du1Jiren Wang1Lixue Zhang1Yu Wang1Mengqi Huang1Nannan Zhu1Huizhong Gan4Hao Ding1*Qiao Mei1*- 1First Affiliated Hospital of Anhui Medical University, Hefei, China
- 2Jinzhai County People's Hospital, Lu'an, China
- 3Taihe County People's Hospital, Fuyang, China
- 4Third Affiliated Hospital of Anhui Medical University, Hefei, China
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To investigate the effect of enteral nutrition (EN) on peripancreatic exudate in MSAP and SAP patients using CT volume measurement. This retrospective study included 328 patients diagnosed with MSAP and SAP from October 2017 to June 2023. Patients were divided into EN and non-EN groups and further stratified into acute peripancreatic fluid collection (APFC) and acute necrotic collection (ANC) groups based on local complications. Abdominal CT images obtained within 24 hours of admission and within 15 days after therapy were analyzed using Itk-Snap software to outline and calculate peripancreatic exudate volumes. Volume differences before and after therapy were compared between groups. A one-year follow-up was conducted to compare the time of complete resolution of peripancreatic exudate between groups. After EN therapy, patients have significantly less peripancreatic exudate than those who do not receive EN. In the APFC and ANC groups, EN was associated with a greater reduction in exudate than that in the non-EN group. The time to complete resolution of exudate was shorter in the EN group than in the non-EN group. EN promotes the absorption of peripancreatic exudate and improves the prognosis of patients with MSAP and SAP.
Keywords: acute pancreatitis, Local complications, Enteral Nutrition, Peripancreatic, exudate volume, computed tomography
Received: 06 Jul 2025; Accepted: 08 Sep 2025.
Copyright: © 2025 Hu, Tian, Chen, Huang, Li, Gao, Du, Wang, Zhang, Wang, Huang, Zhu, Gan, Ding and Mei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hao Ding, First Affiliated Hospital of Anhui Medical University, Hefei, China
Qiao Mei, First Affiliated Hospital of Anhui Medical University, Hefei, China
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