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ORIGINAL RESEARCH article

Front. Med.

Sec. Intensive Care Medicine and Anesthesiology

This article is part of the Research TopicChallenges and Innovations in Healthcare Management and Long-Term Care for an Aging SocietyView all 33 articles

The Impact of Preoperative Nutritional Status, Intraoperative Fluid Administration Volume, Operating Room Temperature, and Anesthesia Duration on Intraoperative Hypothermia in Elderly Patients Undergoing Total Joint Replacement Under General Anesthesia: A Logistic Regression Analysis and Nursing Intervention Strategies

Provisionally accepted
Mingming  LuMingming LuTingting  LiuTingting LiuJian  WangJian WangLiu  WangLiu Wang*Hui  NiHui Ni
  • Nanjing Tongren Hospital, Jiangsu, Nanjing, China

The final, formatted version of the article will be published soon.

To analyze the factors associated with intraoperative hypothermia (IHC) in elderly patients undergoing total joint replacement under general anesthesia based on preoperative nutritional status, intraoperative fluid administration volume, operating room temperature, and anesthesia duration, and to construct and validate a risk prediction model.A retrospective study was conducted on 120 elderly patients who underwent joint replacement surgery at our hospital between March 2023 and March 2025. All patient data were obtained from the electronic medical record system, and patients were divided into an IHC group and a non-IHC group based on whether they experienced IHC. Patient-related data were collected and compared. Selection operator (LASSO) regression analysis and multivariate logistic analysis were performed to identify risk factors for IHC in elderly patients undergoing joint replacement surgery.A total of 120 elderly patients who underwent joint replacement surgery at our hospital were included in this study. According to medical record system records, 21 patients developed IHC, accounting for 17.50%, and were included in the IHC group. Ninety-nine patients did not develop IHC, accounting for 82.50%, and were included in the non-IHC group. There were significant statistical differences between the IHC group and the non-IHC group in terms of BMI, intraoperative fluid administration volume, operating room temperature, anesthesia duration, serum albumin (ALB), and total protein (TP) (P < 0.05). After LASSO regression analysis, none of the above indicators exhibited multicollinearity or overfitting. Logistic regression analysis revealed that intraoperative fluid administration volume and anesthesia duration were risk factors for IHC in elderly joint replacement surgery patients (OR = 1.002, 142.629, P < 0.05), Operating room temperature and ALB were protective factors for IHC in elderly joint replacement surgery patients (OR = 0.626, 0.712, P < 0.05)There are numerous factors associated with the occurrence of IHC in elderly patients undergoing joint replacement surgery, primarily including intraoperative fluid administration volume, operating room temperature, anesthesia duration, and ALB. The risk prediction nomogram model constructed based on these factors demonstrates certain predictive value for the risk of IHC occurrence. Clinically, early screening of high-risk populations and implementation of targeted nursing interventions hold significant implications for clinical outcomes.

Keywords: Elderly, Joint replacement surgery, general anesthesia, Intraoperative hypothermia, Nutritional Status

Received: 12 Aug 2025; Accepted: 06 Nov 2025.

Copyright: © 2025 Lu, Liu, Wang, Wang and Ni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Liu Wang, 15950535486@163.com

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