ORIGINAL RESEARCH article
Front. Med.
Sec. Hematology
Predictive Value of Stress Hyperglycemia Ratio for Perioperative Hidden Blood Loss in Patients with Hip Fractures: A Retrospective Cohort Study
Provisionally accepted
- Beijing Jishuitan Hospital, Beijing, China
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Objective: To investigate the predictive value of stress hyperglycemia ratio (SHR) for perioperative hidden blood loss (HBL) in patients with hip fractures. Methods: A retrospective analysis was conducted on 152 patients with hip fractures admitted to our hospital from January 2021 to December 2023. Patients were divided into an HBL group (n=52) and a non-HBL group (n=100) based on the occurrence of HBL during the perioperative period. Univariate and binary Logistics regression analyses were used to identify influencing factors. The receiver operating characteristic (ROC) curve was employed to evaluate the predictive value of SHR for perioperative HBL in hip fracture patients. Results: There were statistically significant differences (P<0.05) in terms of BMI, osteoporosis, SHR, surgical time, and postoperative drainage between the two groups. Binary Logistics regression analysis indicated that surgical time, postoperative drainage, and SHR were independent influencing factors for perioperative HBL in hip fracture patients (P<0.05). The ROC analysis revealed an area under the curve (AUC) of 0.911, with a standard error of 0.024 (95% CI: 0.865~0.958) and a Youden index of 0.65. At this threshold, the sensitivity was 71.22%, and the specificity was 94.00%. Patients with SHR<1.18 had higher EQ-5D scores, Hct, Hb, PLT, and RBC compared to those with SHR≥1.18. Additionally, complications, length of hospital stay, readmission rates, CRP, APTT, and PT were lower in the SHR<1.18 group, with statistically significant differences (P<0.05). Conclusion: SHR demonstrates a certain predictive value for perioperative HBL in patients with hip fractures, suggesting its inclusion in evaluation models.
Keywords: Stress hyperglycemia ratio, Hip fracture, Hidden blood loss, SHR, HBL
Received: 08 Aug 2025; Accepted: 14 Nov 2025.
Copyright: © 2025 Jia, Huo, Yang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yunyang Jia, beautiful6504@sina.com
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