CASE REPORT article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1685952
Varix of the Vortex Vein Ampulla: A Case Report and Imaging Correlation
Provisionally accepted- XinJiang 474 hospital, Urumqi, China
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Background: We report a case of Varix of the Vortex Vein Ampulla (VVVA) in the right eye. VVVA is relatively rare and often presents as a fundus mass-like lesion during clinical examination, making it easily confused with choroidal tumors. This case report aims to improve ophthalmologists' understanding of this rare lesion and provide a reference for clinical diagnosis and management. Case Presentation: A 29-year-old male presented with 1 month of decreased vision in the right eye. His best-corrected visual acuity was 20/20. B-scan ultrasonography and optical coherence tomography (OCT) revealed a choroidal space-occupying lesion. Fundus examination identified a deep red elevated mass at the inferotemporal VVVA of the right eye. Further indocyanine green (ICG) angiography confirmed VVVA. The mass became more prominent when the patient gazed downward with the right eye. After applying pressure to the eye, follow-up B-scan and OCT showed the mass had disappeared or reduced— findings that strongly confirmed the lesion was VVVA rather than a choroidal tumor. Conclusions: VVVA is an uncommon condition. This case reminds ophthalmologists to consider less common causes when evaluating choroidal mass-like lesions. Accurate diagnosis of VVVA is critical to avoid misdiagnosis as a choroidal tumor and unnecessary invasive testing or treatment. Recognition of this benign condition can prevent misdiagnosis as a choroidal tumor and unnecessary invasive testing.
Keywords: Vortex vein, varix of vortex vein ampulla, Choroid, ICGA, Pressure
Received: 14 Aug 2025; Accepted: 08 Oct 2025.
Copyright: © 2025 Niu and Xiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Tong Tong Niu, nttongsuda@163.com
Yun Xiao, yunxiao2688@126.com
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