CASE REPORT article
Front. Med.
Sec. Nephrology
This article is part of the Research TopicCritical Cases in Clinical NephrologyView all 5 articles
Acute Kidney Injury from Chromium Exposure: Clinical Insights
Provisionally accepted
- 1The First People's Hospital of Yongkang, Yongkang, China
- 2Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China
- 3Zhejiang-Denmark Joint Laboratory of Regeneration and Aging Medicine, Yiwu, China
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Abstract: This article reports a case of a patient who developed nausea, vomiting, and diarrhea, succeeded by oliguria and acute kidney injury, after exposure to a chromium-containing additive pool water while working, followed by oliguria and acute kidney injury. The patient was diagnosed with acute kidney injury, third-degree skin burns, and gastroenteritis. Subsequently, the patient was treated with antioxidant stress management, hemodialysis, and surgical debridement with skin grafting. After one year, the patient's condition gradually improved. In addition, renal biopsy pathology suggested acute interstitial nephritis. In combination, with the medical history and blood chromium monitoring, its kidney pathology was confirmed to be caused by heavy metal chromium poisoning. This case highlights the importance of obtaining a clear history of high exposure to heavy metals for the diagnosis of acute kidney injury, and early active treatment can improve the success rate of rescue.
Keywords: Acute Kidney Injury, Chromium poisoning, case report, literature review,, Kidney Diseases
Received: 26 Aug 2025; Accepted: 27 Nov 2025.
Copyright: © 2025 Xu, Chen, Shi and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Linlin Xu
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