ORIGINAL RESEARCH article
Front. Med.
Sec. Hematology
Relationship between different blood routine parameters and different types of sudden deafness and prognosis
Provisionally accepted
- 1Zhengzhou University People's Hospital, Zhengzhou, China
- 2People's Hospital of Henan University, Zhengzhou, China
- 3Henan Provincial People's Hospital, Henan, China
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This retrospective observational analysis examined the relationship of blood routine parameters and audiometric subtypes of Sudden sensorineural hearing loss and prognosis. The 379 participants were then divided into groups according to audiometric configuration, and time of onset of symptoms and prognosis at 4 weeks after therapy. Hemoglobin, Neutrophilia, Lymphopenia, Monocytosis, Thrombocytosis, and Hypoalbuminemia were positively associated to prognosis while Lymphocytosis, Platelet count, Age, Gender, ASA physical status, Obesity, Chronic illnesses, Chronic kidney disease, Diabetes Mellitus, Hypertension, Dyslipidemia, and Smoking were inversely associated. The independent predictive biomarker was identified as Neutrophil to Lymphocyte Ratio after adjusting for the other indices, such as C-reactive protein and erythrocyte sedimentation rate. Finally, we examined the relationships between the recovery prognosis and symptom onset time, corticosteroid use, and hearing loss. The results have highlighted that combinational assessment with hematological and inflammatory markers will provide better prognosis prediction and enhance the SSNHL treatment approaches.
Keywords: SS carnage, prognosis, Blood routine parameter, Inflammation, biomarkers
Received: 29 Aug 2025; Accepted: 26 Nov 2025.
Copyright: © 2025 Zhang, Wang, Liu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Guangke Wang
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