STUDY PROTOCOL article
Front. Med.
Sec. Pulmonary Medicine
Effects of multi-modal intensive rehabilitation program (MIRP) in lung transplant recipients: study protocol of a pragmatic randomized controlled trial
Provisionally accepted
- China-Japan Friendship Hospital, Beijing, China
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Background The main purpose of this study is to describe a protocol to compare the effectiveness of MIRP and conventional rehabilitation treatment. Methods/design The study will be a single-blinded pragmatic randomized controlled trial involving patients(N=100) with lung transplant. All patients will receive 6 weeks treatment, while they will be divided into two groups and receive MIRP(n=50), conventional rehabilitation treatment(n=50). Clinical functional assessment will be performed before, after intervention, and 3 months after the enrollment respectively. Adults who have undergone unilateral or bilateral lung transplants and have just returned to the regular ward from the intensive care unit are eligible to participate. Discussion The outcome of this study will provide a theoretical basis for clarifying intensive rehabilitation for lung transplant in future studies and clinical practice.
Keywords: Lung transplant (LTx), Rehabilitation, multi-modal intensive, randomized controlled trial, study protocol
Received: 31 Aug 2025; Accepted: 24 Oct 2025.
Copyright: © 2025 Wang, Zhao, Gao, Duan, Zheng, Wang, Chen and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Shan Jiang, landjiang@126.com
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