ORIGINAL RESEARCH article
Front. Med.
Sec. Obstetrics and Gynecology
This article is part of the Research TopicCutting-Edge Strategies in Screening, Prevention, and Treatment in Gynaecologic OncologyView all 42 articles
Comparison of Sexual Function in Women with Endometrial Cancer and Their Partners Following Surgery versus Surgery Additional Brachytherapy: A Cross-Sectional Study from a Tertiary Care Center
Provisionally accepted
Gazi Güner1,2*
Can Tercan1
Emrah Dağdeviren1Ayşe Bacaksiz1Erdem Kıray1Sure Nur Erdoğmuş1
Yahya Özgün Öner1Sinem Özşahin Kılıç1Zeliha Zeynep Satılmışoğlu1Çisem Ertok1
Ergün Tercan3
Figen Efe Çamili4Nazlı Aylin Vural5Ayben Yentek Balkanay1İlkbal Temel Yüksel1
Selcuk Erkilinc6- 1Basaksehir Cam and Sakura City Hospital, Istanbul, Türkiye
- 2Saglik Bilimleri Universitesi, Istanbul, Türkiye
- 3TC Saglik Bakanligi Manisa Merkezefendi Devlet Hastanesi, Yunusemre, Türkiye
- 4Balikesir Universitesi Tip Fakultesi, Balikesir, Türkiye
- 5TC Saglik Bakanligi Yozgat Sehir Hastanesi, Yozgat, Türkiye
- 6TC Saglik Bakanligi Buca Seyfi Demirsoy Egitim ve Arastirma Hastanesi, Buca, Türkiye
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ABSTRACT Background: This study aimed to compare female sexual function and male partner sexual satisfaction between endometrial cancer patients treated with surgery alone and those receiving additional brachytherapy.. Methods: Sixty-nine patients were included. Group 1 (n=34) received adjuvant brachytherapy after surgery; Group 2 (n=35) underwent surgery only. Participants completed a structured questionnaire including socio-demographic and clinical data, along with validated instruments: the Female Sexual Function Index and the New Sexual Satisfaction Scale for partners. Results: The mean age was significantly higher in the brachytherapy group (61.71 ± 7.88 vs. 56.54 ± 8.74 years; p=0.012). Gravidity (p=0.029) and parity (p=0.013) were also higher in this group, while body mass index was similar (p=0.118). Female sexual function index scores [2 (2–20.3) vs. 2 (2–19.6); p=0.459] and new sexual satisfaction scale scores [20 (20–83) vs. 20 (20–90); p=0.492] showed no significant differences. Female sexual function index subdomain scores were also comparable. Tumor grade and stage significantly differed between groups, as did surgical approach and lymphadenectomy rates. Conclusion: Sexual function was negatively affected in all endometrial cancer patients, with a more pronounced impact among those receiving brachytherapy and their partners. These findings highlight the need to consider sexual health in treatment planning and to implement supportive interventions such as psychosexual counseling, particularly for patients undergoing adjuvant radiotherapy.
Keywords: endometrial cancer, Brachytherapy, Sexual function, Female Sexual Function Index (FSFI), New Sexual Satisfaction Scale (NSSS), Partner satisfaction, gynecologic oncology, Quality of Life
Received: 03 Sep 2025; Accepted: 10 Nov 2025.
Copyright: © 2025 Güner, Tercan, Dağdeviren, Bacaksiz, Kıray, Erdoğmuş, Öner, Kılıç, Satılmışoğlu, Ertok, Tercan, Efe Çamili, Vural, Yentek Balkanay, Temel Yüksel and Erkilinc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Gazi Güner, dr.gaziguner01@gmail.com
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