ORIGINAL RESEARCH article
Front. Med.
Sec. Family Medicine and Primary Care
This article is part of the Research TopicAI with Insight: Explainable Approaches to Mental Health Screening and Diagnostic Tools in HealthcareView all 10 articles
Explainable AI for Suicide Risk Detection: Gender-and Age-Specific Patterns from Real-Time Crisis Chats
Provisionally accepted- 1Ruppin Academic Center, Hefer Valley, Israel
- 2University of Haifa Faculty of Education, Haifa, Israel
- 3Ben-Gurion University of the Negev, Be'er Sheva, Israel
- 4Sahar online mental support, Tel Aviv, Israel
- 5Sahar online mental health support, Tel Aviv, Israel
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Background: Suicide remains a leading cause of death worldwide, yet conventional risk models based on static demographic or diagnostic factors show limited predictive value. Advances in explainable artificial intelligence (AI) and natural language processing (NLP) offer new opportunities for real-time, personalized risk detection. Methods: We analyzed 17,564 chat sessions (2017–2021) from Sahar, a digital crisis helpline. Suicide risk (SR) was defined by explicit suicidal ideation. A theory-driven lexicon of 20 psychological constructs (e.g., hopelessness, loneliness, self-harm), derived from leading SR frameworks, was applied using NLP. Logistic regression models estimated associations between constructs and SR, stratified by gender and age (10–17, 18–20, 21–40, 41+). Temporal trajectories of predictors were examined across five conversation stages. Results: Previous suicide attempts and hopelessness were the strongest predictors across all groups. Gender differences emerged: among women, loneliness was a consistent predictor, whereas in men, thwarted belongingness and late-session depression were more salient. Age analyses showed developmental specificity: prior attempts were strongest in adolescents, hopelessness and self-harm peaked in young adults, thwarted belongingness strengthened with age, and loneliness predicted risk only among adults aged 41+. Several factors, including bullying/cyberbullying, LGBTQ identity, and perfectionism, were inversely associated with SR in specific subgroups. Conclusions: This study demonstrates how explainable, theory-informed NLP can capture dynamic SR factors in real-world crisis interactions. Findings reveal distinct gender-and age-specific pathways, underscoring the need for personalized prevention strategies. Beyond theoretical insights, the approach highlights the potential of AI-driven, interpretable monitoring tools to support crisis counselors in detecting escalating risk earlier and tailoring interventions. Such methods can enhance the accuracy, timeliness, and equity of suicide prevention, and illustrate how explainable AI can translate psychological theory into clinically meaningful tools for mental health screening and early intervention.
Keywords: Explainable AI, Natural Language Processing, suicide prevention, crisis helpline, genderand age differences
Received: 11 Sep 2025; Accepted: 26 Nov 2025.
Copyright: © 2025 Grimland, Liberman, Yeshayahu, Benatov, Munz, Segal, Ben Dayan, Shenfeld, Gal and Levi-Belz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Meytal Grimland
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