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CASE REPORT article

Front. Med.

Sec. Dermatology

Case Report: An Unexpected Diagnosis of Cutaneous Mycobacterium marinum Infection Based on Potato Dextrose Agar Culture

Provisionally accepted
Xiujiao  XiaXiujiao Xia1,2*Jiajia  LiJiajia Li2Zehu  LiuZehu Liu2
  • 1Dermatology, Hangzhou Third Hospital, Zhejiang University, Hangzhou, China
  • 2Third People's Hospital of Hangzhou, Hangzhou, China

The final, formatted version of the article will be published soon.

Nontuberculous mycobacteria (NTM) are slender, nonmotile, acid-fast bacilli widely distributed in diverse environmental reservoirs across the globe. In recent years, the incidence of NTM-related diseases has risen significantly, leading to their recognition as major emerging human pathogens. Cutaneous NTM infections typically arise following traumatic injury, surgical intervention, or cosmetic procedures. Due to their heterogeneous clinical presentations, these infections often pose diagnostic challenges. Löwenstein-Jensen medium and Middlebrook medium are widely employed in mycobacterial microbiology and are capable of supporting the growth of most NTM. However, their high cost and limited availability pose significant challenges for implementation in resource-limited settings (RLS). Previously, we successfully isolated a strain of Mycobacterium marinum from a clinical sample using potato dextrose agar (PDA) medium. This finding suggests that PDA may be applicable for the primary culture of NTM, particularly M. marinum. For RLS, this medium could represent a beneficial alternative to traditional mycobacterial culture media.

Keywords: Nontuberculous Mycobacteria, culture, Potato dextrose agar, Cutaneous infection, diagnosis

Received: 20 Sep 2025; Accepted: 28 Oct 2025.

Copyright: © 2025 Xia, Li and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xiujiao Xia, 804534095@qq.com

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