ORIGINAL RESEARCH article
Front. Med.
Sec. Dermatology
This article is part of the Research TopicUpdate in Trichology and Hair TransplantationView all 3 articles
Patients Treated with Thinner Artificial Hair Implants: A case series
Provisionally accepted
- 1University of Studies G. d'Annunzio Chieti and Pescara, Chieti, Italy
- 2Universita degli Studi Gabriele d'Annunzio Chieti Pescara Dipartimento di Tecnologie Innovative in Medicina & Odontoiatria, Chieti, Italy
- 3Policlinico di Modena, Modena, Italy
- 4Universidad Catolica San Antonio de Murcia, Murcia, Spain
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BACKGROUND: Artificial biocompatible hair implants have been developed and clinically evaluated as a solution for hair loss, utilizing various materials and techniques to optimize safety, efficacy, and patient satisfaction. The primary objective of this study was to assess patient satisfaction in individuals affected by alopecia and treated with Biofibre® 4.0, focusing on scalp hair density and aesthetic perception using a four-level evaluation scale. The secondary objective was to evaluate the rate of implanted hair loss at the one-year follow-up. MATERIAL AND METHODS: 15 patients of different ethnicity, 10 men and 5 women were enrolled. Polyamide biofibers with a diameter of 0.08 mm and a length between 160 and 460 mm (Biofibre®, Medicap®, Carpi, Italy) were utilized in the present study. The root of each fiber was positioned beneath the scalp, at the level of the galea aponeurotica. RESULTS: The biocompatibility was excellent without allergies or significant "foreign body" skin reactions. Analysis based on the primary effectiveness endpoint revealed a mean score of 3.1 on a 4-point grading scale, where: 1 = not satisfied (1 patient), 2 = somewhat satisfied (2 patients), 3 = satisfied (7 patients), and 4 = very satisfied (5 patients). DISCUSSION: The 2 implantation of new, thinner artificial hair represents a valid and safe technique. Tolerability has improved thanks to the increased softness and elasticity of these fibers. CONCLUSIONS: In conclusion, the results of this clinical study case series confirm the efficacy and safety of the new Biofibre® in the treatment of both male and female androgenetic alopecia, offering a well-tolerated and effective solution for improving aesthetic appearance and psychological well-being. In conclusion, despite the small sample size, the results of this case series confirm the efficacy and safety of the new Biofibre® in the treatment of both male and female androgenetic alopecia, offering a well-tolerated and effective solution for improving aesthetic appearance and psychological well-being.
Keywords: Hair implant, Hair surgery, Alopecia, FUT, PRP, LED, Biofibre, Baldness
Received: 02 Oct 2025; Accepted: 31 Oct 2025.
Copyright: © 2025 Scarano, Palmieri, Vadalà and Gehrke. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Antonio Scarano, ascarano@unich.it
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