EDITORIAL article
Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
This article is part of the Research TopicAdvances in Intra-Abdominal InfectionView all 6 articles
Editorial: Advances in Intra-Abdominal Infection
Provisionally accepted
- Sir Run Run Shaw Hospital, School of Medicine, Graduate School, Zhejiang University, Hangzhou, China
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The accurate identification of high-risk patients and early warning of IAI are paramount for improving outcomes. A study by Ding et al. investigating liver abscess following thermal ablative therapy for liver cancer identified diabetes mellitus (OR=3.215), a history of abdominal surgery (OR=2.810), biliary tract disease (OR=18.832, demonstrating the strongest correlation), and elevated alkaline phosphatase (ALP) levels (OR=1.010) as independent risk factors. Elucidating the microbiological profile of IAI is essential for guiding appropriate antimicrobial use. Microbiological analysis of liver abscesses following thermal ablation for liver cancer revealed that Gram-negative bacteria accounted for 75.6% of 78 pathogenic strains isolated, with Escherichia coli (30.8%) and Klebsiella pneumoniae (20.5%) being the most prevalent. These two pathogens exhibited high susceptibility to amikacin, cefoxitin, imipenem, among others.However, the positive rates for extended-spectrum beta-lactamase (ESBL) production were 41.2% and 21.1%, respectively, underscoring the necessity for Treatment strategies for various types of IAI have been further refined based on clinical evidence. For ERCP-related Stapfer type IV injury, the simple defect itself is not considered a "true perforation," and conservative management (e.g., anti-infective therapy, gastrointestinal decompression) is feasible. However,
Keywords: Intra-abdominal infection, Risk factor identification, Antimicrobial therapy, Nursing interventions, treatment strategies
Received: 06 Nov 2025; Accepted: 07 Nov 2025.
Copyright: © 2025 Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Feng Guo, 3408003@zju.edu.cn
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