Frontiers in Medicine | Precision Medicine

Original Research

Published on 12 May 2023

Early detection of Parkinson’s disease through enriching the electronic health record using a biomedical knowledge graph

in Precision Medicine

Karthik Soman
Charlotte A. Nelson
Gabriel Cerono
Samuel M. Goldman
Sergio E. Baranzini
Ethan G. Brown

Frontiers in Medicine

doi 10.3389/fmed.2023.1081087

7,489 views
15 citations

Original Research

Published on 12 May 2023

Immune checkpoint inhibitors efficacy across solid cancers and the utility of PD-L1 as a biomarker of response: a systematic review and meta-analysis

in Precision Medicine

Timothy S. Fitzsimmons
Niharika Singh
Thomas D. J. Walker
Claire Newton
Dafydd G. R. Evans
Emma J. Crosbie
Neil A. J. Ryan

Frontiers in Medicine

doi 10.3389/fmed.2023.1192762

8,011 views
26 citations

Editorial

Published on 12 May 2023

Editorial: Personalized medicine and infectious disease management

in Precision Medicine

Sondes Haddad-Boubaker
Hamdi Mbarek
Hadi M. Yassine

Frontiers in Medicine

doi 10.3389/fmed.2023.1191147

2,943 views
2 citations

Original Research

Published on 11 May 2023

Region-specific deep learning models for accurate segmentation of rectal structures on post-chemoradiation T2w MRI: a multi-institutional, multi-reader study

in Precision Medicine

Thomas DeSilvio
Jacob T. Antunes
Kaustav Bera
Prathyush Chirra
Hoa Le
David Liska
Sharon L. Stein
Eric Marderstein
William Hall
Rajmohan Paspulati

Frontiers in Medicine

doi 10.3389/fmed.2023.1149056

2,959 views
7 citations

Case Report

Published on 09 May 2023

A novel homozygous variant of TMEM260 induced cardiac malformation and neurodevelopmental abnormality: case report and literature review

in Precision Medicine

Mou Peng
Siyuan Jing
Sichen Duan
Guoyan Lu
Kaiyu Zhou
Yimin Hua
Tao Wang
Peng Yue
Yifei Li

Frontiers in Medicine

doi 10.3389/fmed.2023.1157042

2,647 views
6 citations

Original Research

Published on 05 May 2023

Rare variant burden analysis from exomes of three consanguineous families reveals LILRB1 and PRSS3 as potential key proteins in inflammatory bowel disease pathogenesis

in Precision Medicine

Rana Mohammed Jan
Huda Husain Al-Numan
Nada Hassan Al-Twaty
Nuha Alrayes
Hadeel A. Alsufyani
Meshari A. Alaifan
Bakr H. Alhussaini
Noor Ahmad Shaik
Zuhier Awan
Yousef Qari

Frontiers in Medicine

doi 10.3389/fmed.2023.1164305

3,567 views
3 citations

Case Report

Published on 04 May 2023

Case report: A combined immunotherapy strategy as a promising therapy for MSI-H colorectal carcinomas with multiple HPD risk factors

in Precision Medicine

Jinli Zhang
Lu Yang
Fanwei Kong
Di Wu
Baoru Hu
Jie Yang
Jiaxin He
Lei Liu

Frontiers in Medicine

doi 10.3389/fmed.2023.1051034

2,929 views
1 citation

Original Research

Published on 04 May 2023

DRSN4mCPred: accurately predicting sites of DNA N4-methylcytosine using deep residual shrinkage network for diagnosis and treatment of gastrointestinal cancer in the precision medicine era

in Precision Medicine

Xia Yu
Jia Ren
Yani Cui
Rao Zeng
Haixia Long
Cuihua Ma

Frontiers in Medicine

doi 10.3389/fmed.2023.1187430

1,497 views
5 citations

Original Research

Published on 03 May 2023

Clinically practical pharmacometrics computer model to evaluate and personalize pharmacotherapy in pediatric rare diseases: application to Graves' disease

in Precision Medicine

Britta Steffens
Gilbert Koch
Pascal Gächter
Fabien Claude
Verena Gotta
Freya Bachmann
Johannes Schropp
Marco Janner
Dagmar l'Allemand
Daniel Konrad

Frontiers in Medicine

doi 10.3389/fmed.2023.1099470

2,517 views
2 citations

Case Report

Published on 03 May 2023

Case report: A novel 5'-UTR-exon1-intron1 deletion in MLYCD in an IVF child with malonyl coenzyme A decarboxylase deficiency and literature review

in Precision Medicine

Fang Xu
Yangyang Wu
Jiyi Huang
Yunguo Zhou
Fei Xu
Junkai Duan
Hong Li

Frontiers in Medicine

doi 10.3389/fmed.2023.1160879

1,890 views

Original Research

Published on 28 Apr 2023

Single cell analysis of the localization of the hematopoietic stem cells within the bone marrow architecture identifies niche-specific proliferation dynamics

in Precision Medicine

Maria Mazzarini
Francesca Arciprete
Orietta Picconi
Mauro Valeri
Paola Verachi
Fabrizio Martelli
Anna Rita Migliaccio
Mario Falchi
Maria Zingariello

Frontiers in Medicine

doi 10.3389/fmed.2023.1166758

3,670 views
2 citations

Review

Published on 27 Apr 2023

Idiopathic pulmonary fibrosis and the role of genetics in the era of precision medicine

in Precision Medicine

Aitana Alonso-Gonzalez
Eva Tosco-Herrera
Maria Molina-Molina
Carlos Flores

Frontiers in Medicine

doi 10.3389/fmed.2023.1152211

12,703 views
15 citations

Original Research

Published on 25 Apr 2023

Application of DCE-MRI radiomics signature analysis in differentiating molecular subtypes of luminal and non-luminal breast cancer

in Precision Medicine

Ting Huang
Bing Fan
Yingying Qiu
Rui Zhang
Xiaolian Wang
Chaoxiong Wang
Huashan Lin
Ting Yan
Wentao Dong

Frontiers in Medicine

doi 10.3389/fmed.2023.1140514

2,266 views
11 citations

Editorial

Published on 18 Apr 2023

Editorial: Rising stars in precision medicine 2021: imprecise medicine is unethical in the big data era

in Precision Medicine

David S. Liebeskind

Frontiers in Medicine

doi 10.3389/fmed.2023.1181788

1,961 views
2 citations

Original Research

Published on 17 Apr 2023

Using quantitative single molecule localization microscopy to optimize multivalent HER2-targeting ligands

in Precision Medicine

Devin L. Wakefield
Ottavia Golfetto
Raphael Jorand
Sunetra Biswas
Kassondra Meyer
Kendra N. Avery
Cindy Zer
Eliedonna E. Cacao
Steven J. Tobin
Ian J. Talisman

Frontiers in Medicine

doi 10.3389/fmed.2023.1064242

2,623 views
2 citations

Original Research

Published on 17 Apr 2023

An autophagy-related diagnostic biomarker for uterine fibroids: FOS

in Precision Medicine

Lei Cai
Jie Li
Rui Long
Zhiqi Liao
Juejun Gong
Bowen Zheng
Hanwang Zhang

Frontiers in Medicine

doi 10.3389/fmed.2023.1153537

2,762 views
3 citations