Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Original Research

Published on 23 Nov 2023

Secreted protein acidic and rich in cysteine (SPARC) induces apoptosis of human brain vascular smooth muscle cells through regulating HK2 in intracranial aneurysm

in Brain Disease Mechanisms

Donglin Zhou
Tao Li
Xianjun Tan
Chenping Yun
Peng Jiang
Tongfu Zhang
Hong Kuang
Yunyan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1290556

3,319 views
3 citations

Original Research

Published on 23 Nov 2023

Characterization of a de novo GABBR2 variant linked to autism spectrum disorder

in Brain Disease Mechanisms

Noa Bielopolski
Michal Stawarski
Ilana Roitman
Karen Fridman
Shane Wald-Altman
Simon Früh
Bernhard Bettler
Andreea Nissenkorn

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1267343

3,670 views
4 citations

Editorial

Published on 17 Nov 2023

Editorial: The molecular mechanisms and potential drug targets for remyelination and neuroregeneration

in Brain Disease Mechanisms

Aleksandra Rutkowska
Maria Velasco-Estevez
Sinead A. O'Sullivan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1332594

1,719 views

Original Research

Published on 14 Nov 2023

Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus

in Brain Disease Mechanisms

Nicole D. Schartz
Alisha Aroor
Yibo Li
Nicole Pinzón-Hoyos
Amy L. Brewster

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1265944

3,941 views
2 citations

Original Research

Published on 13 Nov 2023

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR

in Brain Disease Mechanisms

Erika Kropf
Arman Shekari
Sama Jaberi
Anish Puri
Chengbiao Wu
Margaret Fahnestock

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1241420

2,566 views
1 citation

Original Research

Published on 09 Nov 2023

The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy

in Brain Disease Mechanisms

Nikhil S. Rao
Marson Putra
Christina Meyer
Aida Almanza
Thimmasettappa Thippeswamy

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1294514

3,219 views
2 citations

Original Research

Published on 09 Nov 2023

Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome

in Brain Disease Mechanisms

Magdalena Chojnacka
Anna Beroun
Marta Magnowska
Aleksandra Stawikowska
Dominik Cysewski
Jacek Milek
Magdalena Dziembowska
Bozena Kuzniewska

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1258615

2,661 views
7 citations

Original Research

Published on 06 Nov 2023

Prominent elevation of extracellular matrix molecules in intracerebral hemorrhage

in Brain Disease Mechanisms

Hongmin Li
Samira Ghorbani
Ruiyi Zhang
Vincent Ebacher
Erin L. Stephenson
Michael B. Keough
V. Wee Yong
Mengzhou Xue

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1251432

4,126 views
6 citations

Original Research

Published on 02 Nov 2023

Increased pituitary adenylate cyclase-activating peptide genes expression in the prefrontal cortex in schizophrenia in relation to suicide

in Brain Disease Mechanisms

Zala Slabe
Rawien A. Balesar
Ronald W. H. Verwer
Gorazd Drevenšek
Dick F. Swaab

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1277958

2,574 views
4 citations

Original Research

Published on 30 Oct 2023

Identification ferroptosis-related hub genes and diagnostic model in Alzheimer’s disease

in Brain Disease Mechanisms

Huabin Zhao
Jiawei Wang
Zhongzheng Li
Shenghui Wang
Guoying Yu
Lan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1280639

5,212 views
6 citations

Original Research

Published on 30 Oct 2023

Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice

in Brain Disease Mechanisms

Xiaoxia Li
Yuan Gao
Baoying Li
Wenqian Zhao
Qian Cai
Wenbin Yin
Shudong Zeng
Xiaoli Li
Haiqing Gao
Mei Cheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1251513

3,216 views
1 citation

Original Research

Published on 27 Oct 2023

Plasma D-dimer levels are a biomarker for in-hospital complications and long-term mortality in patients with traumatic brain injury

in Brain Disease Mechanisms

Xinli Chen
Xiaohua Wang
Yingchao Liu
Xiumei Guo
Fan Wu
Yushen Yang
Weipeng Hu
Feng Zheng
Hefan He

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1276726

2,182 views
3 citations

Original Research

Published on 25 Oct 2023

ADAR1 suppression causes interferon signaling and transposable element transcript accumulation in human astrocytes

in Brain Disease Mechanisms

Cali M. McEntee
Alyssa N. Cavalier
Thomas J. LaRocca

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1263369

3,357 views
3 citations

Original Research

Published on 25 Oct 2023

Whole exome sequencing of patients with varicella-zoster virus and herpes simplex virus induced acute retinal necrosis reveals rare disease-associated genetic variants

in Brain Disease Mechanisms

Johanna L. Heinz
Sigrid M. A. Swagemakers
Joanna von Hofsten
Marie Helleberg
Michelle M. Thomsen
Kerstin De Keukeleere
Joke H. de Boer
Tomas Ilginis
Georges M. G. M. Verjans
Peter M. van Hagen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1253040

3,499 views
3 citations

Original Research

Published on 24 Oct 2023

Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus

in Brain Disease Mechanisms

Fabio Cesar Tescarollo
Daniel Valdivia
Spencer Chen
Hai Sun

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1268311

3,451 views
4 citations

Mini Review

Published on 16 Oct 2023

Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease

in Brain Disease Mechanisms

Gunnar Nordvall
Johan Lundkvist
Johan Sandin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1279740

9,062 views
17 citations