Frontiers in Molecular Neuroscience

Review

Published on 04 Jul 2025

Exosome-mediated miRNA delivery: a molecular switch for reshaping neuropathic pain therapy

in Pain Mechanisms and Modulators

Ziqing Wei
Chunhui Guo
Hang Zhou
Yanling Wu
Xudong Zhou
Jibing Chen
Fujun Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1625943

203 views

Review

Published on 04 Jul 2025

TRP channels in mammalian hearing loss

in Molecular Signalling and Pathways

Zhidong Zhang
Baoshan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1626640

207 views

Review

Published on 02 Jul 2025

The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models

in Molecular Signalling and Pathways

Michael L. Dawes
Jim P. Haberlander
Markus Islinger
Michael Schrader

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1602343

455 views

Systematic Review

Published on 02 Jul 2025

Recognition of the microbial metabolite p-cresol in autism spectrum disorder: systematic review and meta-analysis

in Brain Disease Mechanisms

María Isabel Serrano-Tomás
Paulina Contreras-Romero
Mara Parellada
Javier Chaves-Cordero
Javier Zamora
Martha Hengst
Patricia Pozo
Rosa del Campo
Sheyla Guzmán-Salas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1576388

509 views

Review

Accepted on 01 Jul 2025

Decoding Chronic Pain: The Glutamate-GABA Tug of War in the Cerebral Cortex

in Pain Mechanisms and Modulators

Dan Huang
Yu-Ting Dong
Liu-Xuan He
Rui-Zhu Zhou
Jian-Xiong Zhou
Sha Yang
Shu-Guang Yu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1572775

109 views

Editorial

Published on 01 Jul 2025

Editorial: Come as you R(NA): post-transcriptional regulation will do the rest

in Neuroplasticity and Development

Oriane Mauger
Michael A. Kiebler
Clémence Bernard

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1644067

315 views

Original Research

Accepted on 30 Jun 2025

Chronic reduction of synaptic proteins in the epileptogenic lesion of patients with hippocampal sclerosis

in Brain Disease Mechanisms

Akiko Oota-Ishigaki
Nami Suzuki
Keiya Iijima
Yutaro Takayama
Yuiko Kimura
Kotaro Hattori
Masaki Iwasaki
Takashi Hayashi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1635852

Original Research

Accepted on 26 Jun 2025

Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia

in Molecular Signalling and Pathways

Erick J Martinez-Colin
Ivonne Lezama
Lenin David Ochoa-de La Paz
Monica Lamas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1628860

102 views

Review

Published on 26 Jun 2025

Decoding pain chronification: mechanisms of the acute-to-chronic transition

in Pain Mechanisms and Modulators

Shunwei Zhang
Youzhi Ning
Yiyi Yang
Guo Mu
Yongkui Yang
Changhe Ren
Changli Liao
Cehua Ou
Yue Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596367

540 views

Original Research

Published on 26 Jun 2025

Research hotspots and emerging trends in MicroRNA therapy for neuropathic pain: a bibliometric analysis (2009–2024)

in Pain Mechanisms and Modulators

Yiqiang Zhang
Shushu Chen
Jiangtao Chi
Qinghua Gao
Yujie Li
Huaizhao Wang
Yuanyuan Yu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1610844

394 views

Review

Published on 26 Jun 2025

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

in Brain Disease Mechanisms

Xin-yi Zou
Luo-yang Cai
Jin Zhang
Ying Yuan
Jie Song
Zhao-duan Hu
Xiao-feng Ruan
Rui Peng
Xiao-ming Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1585079

414 views

Original Research

Published on 26 Jun 2025

The potential anti-seizure effects of Astaxanthin-loaded nanostructured lipid carriers in rat model of status epilepticus

in Molecular Signalling and Pathways

Sherien E. Khalaf
Mohammad Al Masri
Ghaleb Oriquat
Maher A. Kamel
Nagwa M. Assem
Suzan M. Abdel-Tawab
Samar S. Elblehi
Shimaa A. Mahmoud

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613893

418 views

Original Research

Accepted on 25 Jun 2025

The role of BET inhibition in modulating amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation

in Brain Disease Mechanisms

Marta Matuszewska
Anna Wilkaniec
Magdalena Gąssowska-Dobrowolska
Magdalena Cieślik
Gabriela Olech-Kochańczyk
Ewelina Pałasz
Elżbieta Gawinek
Marcin Strawski
Grzegorz Arkadiusz Czapski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1619583

124 views

Original Research

Published on 25 Jun 2025

Critical gene network and signaling pathway analysis of the extracellular signal-regulated kinase (ERK) pathway in ischemic stroke

in Brain Disease Mechanisms

Rui Mao
Lei Wang
Haitao Zhang
Jiaojiao Gong
Hua Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1604670

351 views

Review

Published on 25 Jun 2025

How endothelial cell metabolism shapes blood–brain barrier integrity in neurodegeneration

in Brain Disease Mechanisms

Jiaxin Wang
Yuchun Chen
Shiteng Chen
Zihan Mu
Jun Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1623321

467 views

Original Research

Published on 25 Jun 2025

Whole-genome sequencing shows modulation of neurodegenerative genes by Withania somnifera in human SK-N-SH cells

in Brain Disease Mechanisms

Eshita Sharma
Dilip Mehta
Nikita Jadhav
Gunjan Gujrati
S. Dhananya
Manju Moorthy
Gopalakrishna Ramaswamy
Yundong Zhou
Sujit Nair

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1512727

651 views