Frontiers in Molecular Neuroscience

Original Research

Accepted on 26 Jun 2025

Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia

in Molecular Signalling and Pathways

Erick J Martinez-Colin
Ivonne Lezama
Lenin David Ochoa-de La Paz
Monica Lamas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1628860

Review

Published on 26 Jun 2025

Decoding pain chronification: mechanisms of the acute-to-chronic transition

in Pain Mechanisms and Modulators

Shunwei Zhang
Youzhi Ning
Yiyi Yang
Guo Mu
Yongkui Yang
Changhe Ren
Changli Liao
Cehua Ou
Yue Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596367

331 views

Original Research

Published on 26 Jun 2025

Research hotspots and emerging trends in MicroRNA therapy for neuropathic pain: a bibliometric analysis (2009–2024)

in Pain Mechanisms and Modulators

Yiqiang Zhang
Shushu Chen
Jiangtao Chi
Qinghua Gao
Yujie Li
Huaizhao Wang
Yuanyuan Yu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1610844

252 views

Review

Published on 26 Jun 2025

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

in Brain Disease Mechanisms

Xin-yi Zou
Luo-yang Cai
Jin Zhang
Ying Yuan
Jie Song
Zhao-duan Hu
Xiao-feng Ruan
Rui Peng
Xiao-ming Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1585079

258 views

Original Research

Published on 26 Jun 2025

The potential anti-seizure effects of Astaxanthin-loaded nanostructured lipid carriers in rat model of status epilepticus

in Molecular Signalling and Pathways

Sherien E. Khalaf
Mohammad Al Masri
Ghaleb Oriquat
Maher A. Kamel
Nagwa M. Assem
Suzan M. Abdel-Tawab
Samar S. Elblehi
Shimaa A. Mahmoud

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613893

289 views

Original Research

Accepted on 25 Jun 2025

The role of BET inhibition in modulating amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation

in Brain Disease Mechanisms

Marta Matuszewska
Anna Wilkaniec
Magdalena Gąssowska-Dobrowolska
Magdalena Cieślik
Gabriela Olech-Kochańczyk
Ewelina Pałasz
Elżbieta Gawinek
Marcin Strawski
Grzegorz Arkadiusz Czapski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1619583

Original Research

Published on 25 Jun 2025

Critical gene network and signaling pathway analysis of the extracellular signal-regulated kinase (ERK) pathway in ischemic stroke

in Brain Disease Mechanisms

Rui Mao
Lei Wang
Haitao Zhang
Jiaojiao Gong
Hua Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1604670

267 views

Review

Published on 25 Jun 2025

How endothelial cell metabolism shapes blood–brain barrier integrity in neurodegeneration

in Brain Disease Mechanisms

Jiaxin Wang
Yuchun Chen
Shiteng Chen
Zihan Mu
Jun Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1623321

331 views

Original Research

Published on 25 Jun 2025

Whole-genome sequencing shows modulation of neurodegenerative genes by Withania somnifera in human SK-N-SH cells

in Brain Disease Mechanisms

Eshita Sharma
Dilip Mehta
Nikita Jadhav
Gunjan Gujrati
S. Dhananya
Manju Moorthy
Gopalakrishna Ramaswamy
Yundong Zhou
Sujit Nair

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1512727

470 views

Original Research

Published on 23 Jun 2025

Exploring research trends and hotspots in PI3K/Akt signaling pathway in ischemic stroke: a bibliometric analysis

in Molecular Signalling and Pathways

Yingquan Liu
Yu Ye
Lin Bai
Fan Dai
Xingxing Su
Peijia Hu
Hongliang Cheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613702

411 views

Original Research

Published on 20 Jun 2025

Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway

in Molecular Signalling and Pathways

Haifengqing Li
Fan Zhang
Cong Zhang
Min Zhou
Qing Liu
Guoyong Zeng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1554802

294 views

Review

Published on 20 Jun 2025

Peroxisome dynamics and inter-organelle interactions in neuronal health and disease

in Molecular Signalling and Pathways

Ruth E. Carmichael

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1603632

574 views

Review

Accepted on 19 Jun 2025

Exosome-mediated miRNA Delivery: A Molecular Switch for Reshaping Neuropathic Pain Therapy

in Pain Mechanisms and Modulators

Ziqing Wei
Hang Zhou
Chunhui Guo
Yanling Wu
Xudong Zhou
Chen Jibing
Fujun Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1625943

Original Research

Accepted on 19 Jun 2025

Peripheral gene dysregulation in Negr1-deficient mice: Insights into possible links with affective behavior

in Molecular Signalling and Pathways

Soojin Lee
Abdulkadir Yusif Maigoro
Ara Yoo
Seoyeon Cho

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1602201

106 views

Original Research

Published on 19 Jun 2025

Dysregulation of heterochromatin caused by genomic structural variants may be central to autism spectrum disorder

in Molecular Signalling and Pathways

Michael R. Garvin
David Kainer

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1553575

600 views

Original Research

Published on 18 Jun 2025

Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance

in Brain Disease Mechanisms

Qingqing Xu
Xin Liu
Yibo Zhang
Shiyu Yuan
Wenli Huang
Mingshan Pi
Qi Xiong
Hongyan Zhou
Yuran Gui
Yifan Xiao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596021

420 views